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      Functional polymorphism of matrix metalloproteinase-9 (MMP-9) gene and response to lithium prophylaxis in bipolar patients.

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          Abstract

          Matrix metalloproteinase 9 (MMP-9) has been implicated in a number of pathological conditions including cancer and heart diseases, and recently also in such neuropsychiatric disorders as schizophrenia and bipolar illness. Therefore, we investigated a possible association between functional polymorphisms of the MMP-9 gene and the response to lithium, the main mood-stabilizing drug in bipolar illness.

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          Author and article information

          Journal
          Hum Psychopharmacol
          Human psychopharmacology
          Wiley
          1099-1077
          0885-6222
          Mar 2011
          : 26
          : 2
          Affiliations
          [1 ] Department of Adult Psychiatry, Poznan University of Medical Sciences, Poland. rybakows@wlkp.top.pl
          Article
          10.1002/hup.1182
          21437990
          58bc27cb-16c8-4318-8909-d742ad14ceaf
          History

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