Individual Differences in Alpha Frequency Drive Crossmodal Illusory Perception

Summary

Perception routinely integrates inputs from different senses. Stimulus temporal proximity critically determines whether or not these inputs are bound together. Despite the temporal window of integration being a widely accepted notion, its neurophysiological substrate remains unclear. Many types of common audio-visual interactions occur within a time window of ∼100 ms [ 1–5]. For example, in the sound-induced double-flash illusion, when two beeps are presented within ∼100 ms together with one flash, a second illusory flash is often perceived [ 2]. Due to their intrinsic rhythmic nature, brain oscillations are one candidate mechanism for gating the temporal window of integration. Interestingly, occipital alpha band oscillations cycle on average every ∼100 ms, with peak frequencies ranging between 8 and 14 Hz (i.e., 120–60 ms cycle). Moreover, presenting a brief tone can phase-reset such oscillations in visual cortex [ 6, 7]. Based on these observations, we hypothesized that the duration of each alpha cycle might provide the temporal unit to bind audio-visual events. Here, we first recorded EEG while participants performed the sound-induced double-flash illusion task [ 4] and found positive correlation between individual alpha frequency (IAF) peak and the size of the temporal window of the illusion. Participants then performed the same task while receiving occipital transcranial alternating current stimulation (tACS), to modulate oscillatory activity [ 8] either at their IAF or at off-peak alpha frequencies (IAF±2 Hz). Compared to IAF tACS, IAF−2 Hz and IAF+2 Hz tACS, respectively, enlarged and shrunk the temporal window of illusion, suggesting that alpha oscillations might represent the temporal unit of visual processing that cyclically gates perception and the neurophysiological substrate promoting audio-visual interactions.

Highlights

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  Peak α frequency predicts temporal windows of the double-flash illusion

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  tACS tuned around α frequency causally modulates this illusory temporal window

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  Slower versus faster tACS α frequencies enlarged versus shrunk the illusory temporal window

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  α peak is the “fingerprint” driving crossmodal impact upon visual processing

Abstract

Multisensory integration occurs within a critical temporal window. Cecere et al. discover the neurophysiological correlates of this phenomenon. Individual oscillatory frequency within the occipital α band causally determines the individual temporal profile of cross-sensory integration, setting the sensory pace of conscious perceptual experience.