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      Epstein-Barr virus DNA is present both in CD10/CD77 positive and negative subsets of human tonsillar lymphocytes.

      1 , , , , ,
      Cancer letters
      Elsevier BV

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          Abstract

          We report the fractionation of freshly isolated subsets of tonsillar lymphocytes according to cell density and double sorting for the differential expression of CD10 and CD77, and their analysis for the presence of Epstein Barr virus genome by nested PCR. All the subsets of tonsillar lymphocytes gave unequivocal evidence for the presence of EBV DNA, when obtained from EBV seropositive individuals. Confirmation of all cases examined demonstrates that B lymphocytes from the germinal centers of tonsils are also involved in carrying the EBV infection in vivo.

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          Author and article information

          Journal
          Cancer Lett.
          Cancer letters
          Elsevier BV
          0304-3835
          0304-3835
          Feb 10 1995
          : 89
          : 1
          Affiliations
          [1 ] Dipartimento di Medicina Sperimentale, Università degli Studi di Roma La Sapienza, Italy.
          Article
          0304-3835(95)90167-1
          10.1016/0304-3835(95)90167-1
          7882294
          59454898-db87-4833-982f-1e8c1baaeabb
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