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      Minimal Change Glomerulonephritis following a Wasp Sting

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          Abstract

          We report the case of a young white male who developed the nephrotic syndrome after being stung by a wasp. A percutaneous renal biopsy was done revealing minimal change glomerulonephritis. The patient was treated with oral prednisone with resolution of proteinuria. Corticosteroids were gradually tapered, the patient did not experience a relapse, and remains in good health with normal renal function. Herein, we also include a review of the literature on wasp bite associated nephrotic syndrome in patients who underwent a renal biopsy.

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          Dialysis or plasmapheresis for acute renal failure due to Africanized honeybee stings.

          M Beccari (1999)
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            Multiple African Honeybee Stings and Acute Renal Failure

            In 1956, the Brazilian government brought honeybees (Apis mellifera andansonii) from South Africa. A group of these bees crossed the Amazon and reached Venezuela where they have killed between 30 and 50 people in the last 4 years [1]. In 1993, we observed the first case of rhabdomyolysis, hepatic dysfunction and acute renal failure (ARF) following multiple stings by African bees (A. mellifera andansonii) in French Guiana.
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              Nephrotic Syndrome with Mesangial Proliferative Glomerulonephritis Induced by Multiple Wasp Stings

              We report the case of a young male who developed severe nephrotic syndrome within 2–3 weeks after being stung by 3 wasps. A percutaneous kidney biopsy specimen revealed mesangioproliferative glomerulonephritis with occasional subepithelial deposits suggestive of early membranous nephropathy. The patient was treated with oral prednisone 60 mg/day with no significant clinical response after 4 weeks, at which point he was started on oral cyclophosphamide, 100 mg/day, while the prednisone dose was tapered to 20 mg every other day over a 2-week period. Six months after initiation of cyclophosphamide, he still has severe nephrotic syndrome. We also briefly review the literature on Hymenoptera sting associated nephrotic syndrome.
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                Author and article information

                Journal
                AJN
                Am J Nephrol
                10.1159/issn.0250-8095
                American Journal of Nephrology
                S. Karger AG
                0250-8095
                1421-9670
                2001
                December 2001
                28 December 2001
                : 21
                : 6
                : 486-489
                Affiliations
                Departments of aMedicine and bPathology, Louisiana State University Health Sciences Center, Shreveport, La., USA
                Article
                46653 Am J Nephrol 2001;21:486–489
                10.1159/000046653
                11799266
                59632a25-2854-4eac-bb34-96951ac1828e
                © 2001 S. Karger AG, Basel

                Copyright: All rights reserved. No part of this publication may be translated into other languages, reproduced or utilized in any form or by any means, electronic or mechanical, including photocopying, recording, microcopying, or by any information storage and retrieval system, without permission in writing from the publisher. Drug Dosage: The authors and the publisher have exerted every effort to ensure that drug selection and dosage set forth in this text are in accord with current recommendations and practice at the time of publication. However, in view of ongoing research, changes in government regulations, and the constant flow of information relating to drug therapy and drug reactions, the reader is urged to check the package insert for each drug for any changes in indications and dosage and for added warnings and precautions. This is particularly important when the recommended agent is a new and/or infrequently employed drug. Disclaimer: The statements, opinions and data contained in this publication are solely those of the individual authors and contributors and not of the publishers and the editor(s). The appearance of advertisements or/and product references in the publication is not a warranty, endorsement, or approval of the products or services advertised or of their effectiveness, quality or safety. The publisher and the editor(s) disclaim responsibility for any injury to persons or property resulting from any ideas, methods, instructions or products referred to in the content or advertisements.

                History
                Page count
                Figures: 2, Tables: 3, References: 21, Pages: 4
                Categories
                Case Report

                Cardiovascular Medicine,Nephrology
                Nephrotic syndrome,Glomerulonephritis,Wasp sting
                Cardiovascular Medicine, Nephrology
                Nephrotic syndrome, Glomerulonephritis, Wasp sting

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