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      Process evaluation of the context, reach and recruitment of participants and delivery of dementia-specific case conferences (WELCOME-IdA) in nursing homes (FallDem): a mixed-methods study

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          Abstract

          Background

          A system of dementia-specific case conferences (WELCOME-IdA) was evaluated using a stepped-wedge design in six nursing homes (NHs) to enable nursing staff to analyse properly the behavioural and psychological symptoms (BPSD) of residents with dementia. A process evaluation of the context, the recruitment and target populations reached (residents and nursing staff) and the delivery of the intervention and implementation strategy was carried out to explore the lack of effectiveness of WELCOME-IdA on the residents’ prevalence of BPSD.

          Methods

          This study was part of a larger process evaluation using a mixed-methods design. Standardised questionnaires, semi-structured interviews, attendance lists, standardised protocols and written self-reports were used to collect the data. The quantitative data were analysed by calculating descriptive statistics. The qualitative interviews were analysed using deductive content analysis and the self-reports were analysed using a documentary analysis.

          Results

          None of the NHs had prior experience with dementia-specific case conferences on a specific concept related to BPSD. The number of residents for whom a dementia-specific case conference was held was lower than expected. The number of nursing staff reached was high, although as defined in the study protocol, core nursing teams continuously participating in all components of the intervention were not established throughout the study. An analysis of the delivery of the intervention showed a reduction in the frequency of dementia-specific case conferences and deviations in the process structure and role structure of WELCOME-IdA. The strategy used to facilitate the implementation of WELCOME-IdA was mostly followed. An analysis of the recruitment of residents indicated that the variation in which residents were included in the study sample was high and that the intended sample size required to achieve a power >80% was not reached.

          Conclusion

          An analysis of the process evaluation data indicated that there were inaccuracies in the implementation of WELCOME-IdA and there were methodological limitations within the design of the effectiveness trial, both of which could explain the lack of effectiveness of WELCOME-IdA. To optimise the process structure of WELCOME-IdA, an assessment of BPSD and a pre-selection of possible domains for the behavioural analysis could be conducted prior to a dementia-specific case conference.

          Trial registration

          ISRCTN20203855. Registered on 10 July 2013.

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          Most cited references25

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          Updated systematic review identifies substantial number of retention strategies: using more strategies retains more study participants.

          The retention of participants in studies is important for the validity of research. We updated our prior systematic review (2005) to assess retention strategies for in-person follow-up in health care studies.
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            The course of neuropsychiatric symptoms in nursing-home patients with dementia over a 53-month follow-up period.

            Neuropsychiatric symptoms (NPS) are prevalent in nursing-home (NH) patients with dementia, but little is known about the long-term course of these symptoms. In this study, 931 NH patients with dementia took part in a prospective cohort study with four assessments over a 53-month follow-up period. NPS and level of dementia were assessed with the Neuropsychiatric Inventory scale and the Clinical Dementia Rating scale, respectively. Mild, moderate, and severe dementia was present in 25%, 33%, and 42%, respectively. There was an increase in the severity of the dementia from the first to the fourth assessment. Agitation, irritability, disinhibition, and apathy were the most prevalent and persistent symptoms during the study period. The affective subsyndrome (depression and anxiety) became less severe, whereas the agitation subsyndrome (agitation/aggression, disinhibition, and irritability) and apathy increased in severity during the follow-up period. More severe dementia was associated with more severe agitation, psychosis, and apathy, but not more severe affective symptoms. Mild dementia was associated with an increase in the severity of psychosis, whereas moderate or severe dementia was associated with decreasing severity of psychosis over the follow-up period. Nearly all the patients experienced clinically significant NPS, but individual symptoms fluctuated. Affective symptoms became less severe, while agitation and apathy increased in severity. An increase in dementia severity was associated with an increase in the severity of agitation, psychosis, and apathy, but not affective symptoms. The results may have implications when planning evaluation, treatment, and the prevention of NPS in NH patients.
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              Determinants of behavioral and psychological symptoms of dementia: A scoping review of the evidence

              Behavioral and psychological symptoms of dementia (BPSD) are prevalent in people with neurodegenerative diseases.
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                Author and article information

                Contributors
                daniela.holle@dzne.de
                rene.mueller-widmer@dzne.de
                sven.reuther@dzne.de
                ute.rosier@uni-wh.de
                rabea.graf@uni-bielefeld.de
                martina.roes@dzne.de
                margareta.halek@dzne.de
                Journal
                Trials
                Trials
                Trials
                BioMed Central (London )
                1745-6215
                14 January 2019
                14 January 2019
                2019
                : 20
                : 45
                Affiliations
                [1 ]ISNI 0000 0004 0438 0426, GRID grid.424247.3, German Center for Neurodegenerative Diseases (DZNE), ; Stockumer Str. 12, 58453 Witten, Germany
                [2 ]ISNI 0000 0000 9024 6397, GRID grid.412581.b, Faculty of Health, , University of Witten/Herdecke, ; Alfred-Herrhausen-Straße 50, 58455 Witten, Germany
                Author information
                http://orcid.org/0000-0002-6563-4712
                Article
                3147
                10.1186/s13063-018-3147-9
                6332590
                30642387
                59d5e1a5-45e2-4342-8603-fbb1a91ba957
                © The Author(s). 2019

                Open AccessThis article is distributed under the terms of the Creative Commons Attribution 4.0 International License ( http://creativecommons.org/licenses/by/4.0/), which permits unrestricted use, distribution, and reproduction in any medium, provided you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons license, and indicate if changes were made. The Creative Commons Public Domain Dedication waiver ( http://creativecommons.org/publicdomain/zero/1.0/) applies to the data made available in this article, unless otherwise stated.

                History
                : 2 August 2018
                : 17 December 2018
                Funding
                Funded by: Public Welfare Foundation of North-Rhine-Westphalia
                Award ID: SW-620-6227-Z
                Award Recipient :
                Categories
                Research
                Custom metadata
                © The Author(s) 2019

                Medicine
                dementia-specific case conference,behavioural and psychological symptoms,process evaluation,nursing home,dementia,mixed-methods study,welcome-ida

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