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      Disposable Sensors in Diagnostics, Food, and Environmental Monitoring

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          Most cited references 240

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          In vitro selection of RNA molecules that bind specific ligands.

          Subpopulations of RNA molecules that bind specifically to a variety of organic dyes have been isolated from a population of random sequence RNA molecules. Roughly one in 10(10) random sequence RNA molecules folds in such a way as to create a specific binding site for small ligands.
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            Continuous cultures of fused cells secreting antibody of predefined specificity.

             G Köhler,  C Milstein (1975)
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              Epidermal electronics.

              We report classes of electronic systems that achieve thicknesses, effective elastic moduli, bending stiffnesses, and areal mass densities matched to the epidermis. Unlike traditional wafer-based technologies, laminating such devices onto the skin leads to conformal contact and adequate adhesion based on van der Waals interactions alone, in a manner that is mechanically invisible to the user. We describe systems incorporating electrophysiological, temperature, and strain sensors, as well as transistors, light-emitting diodes, photodetectors, radio frequency inductors, capacitors, oscillators, and rectifying diodes. Solar cells and wireless coils provide options for power supply. We used this type of technology to measure electrical activity produced by the heart, brain, and skeletal muscles and show that the resulting data contain sufficient information for an unusual type of computer game controller.
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                Author and article information

                Journal
                Advanced Materials
                Adv. Mater.
                Wiley
                0935-9648
                1521-4095
                May 15 2019
                May 15 2019
                : 1806739
                Affiliations
                [1 ]Department of BioengineeringImperial College LondonRoyal School of Mines SW7 2AZ London UK
                [2 ]University of FreiburgFreiburg Center for Interactive Materials and Bioinspired Technologies (FIT) 79110 Freiburg Germany
                [3 ]Laboratory for SensorsDepartment of Microsystems Engineering (IMTEK)University of Freiburg 79110 Freiburg Germany
                [4 ]REQUIMTE/LAQVInstituto Superior de Engenharia do Porto 4249‐015 Porto Portugal
                [5 ]Departamento de Química Física y AnalíticaUniversidad de Oviedo 33006 Oviedo Spain
                [6 ]Catalan Institute of Nanoscience and Nanotechnology (ICN2)CSIC and The Barcelona Institute of Science and Technology 08193 Barcelona Spain
                [7 ]ICREA 08010 Barcelona Spain
                [8 ]Korea Institute of Science and Technology in Europe 66123 Saarbrücken Germany
                [9 ]University of FreiburgFreiburg Materials Research Center (FMF) 79104 Freiburg Germany
                10.1002/adma.201806739
                © 2019

                http://doi.wiley.com/10.1002/tdm_license_1.1

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