We document the taxonomic diversity of medium-sized and large mammals present in Rancho Experimental Teseachi, a teaching and research facility of the Universidad Autónoma de Chihuahua located in the northwestern part of Chihuahua, Mexico. Monthly samplings were made with lineal transects of 5 km in two habitats, open grassland and pine-oak forest, where camera-traps and scent-stations were placed, and tracks were searched. Sixteen species of medium-sized and large mammals were recorded in the area, representing 12.03% of the state’s diversity. The greatest diversity was found in the pine-oak forest. Implementing three different sampling techniques at the same time allows the documentation of mammal diversity more efficiently than using only one or two sampling techniques.