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Calcium and the anionic polypeptide fraction (APF) have opposing effects on cholesterol crystallization in model bile
Fred M. Konikoff ,
Paulette Lechene de la Porte ,
Hara Laufer ,
Nicole Domingo ,
Huguette Lafont ,
Turia Gilat
October 1997
October 1997
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Abstract
Cholesterol gallstones contain both calcium and biliary proteins, but their respective
roles in gallstone pathogenesis are unknown. We have studied the effects of calcium
and a major biliary protein, anionic polypeptide fraction, on the process of cholesterol
crystallization in bile.