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      Evidence for using bisphosphonate to treat Legg-Calvé-Perthes disease.

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          Abstract

          The rationale for using bisphosphonate (BP) therapy for Legg-Calvé-Perthes disease (LCPD) is the potential to prevent substantial femoral head deformity during the fragmentation phase by inhibiting osteoclastic bone resorption. However, it is unclear whether BP therapy decreases femoral head deformity.

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          Author and article information

          Journal
          Clin. Orthop. Relat. Res.
          Clinical orthopaedics and related research
          1528-1132
          0009-921X
          Sep 2012
          : 470
          : 9
          Affiliations
          [1 ] Texas Scottish Rite Hospital for Children, UT Southwestern Medical Center, Dallas, TX, USA.
          Article
          10.1007/s11999-011-2240-0
          22270467
          5a36e598-1c00-47b7-a028-4767d884bcf4
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