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      New zeolite-based composite pads with high-volume blood absorption for early warning of postpartum hemorrhage

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          Abstract

          Medical treatment of severe blood loss during labor is crucial, and the early warning indicator of postpartum hemorrhage (PPH) is essential for labor medical treatment. Measurement of blood loss conventionally looks dirty, reluctant, and less hygienic since some of the blood might be spilled out in the maternity bed, while commercially existing pads have low blood absorption capacity. A new design composite pad composed of absorbent materials, including cellulose rayon, super absorbent polymer (SAP), and zeolite was fabricated and characterized. The SAP and zeolite show properties as crystalline and amorphous materials, respectively. The surface area of natural zeolite was 19.79 (m 2/g). The newly fabricated composite pad showed a high blood absorption capacity (>500–600 mL) with a blood absorption rate of 55.56–85.84 mL/min (depending on the blood volume), showing better performance as compared to the commercial pads. These characteristics suggest that the new composite pad could function not only as a sanitary pad but also as an early warning indicator for PPH if the rate and blood volume reach the dangerous category (≥600 mL or at ≥13 mL/min rate).

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          Biomedical applications of zeolite-based materials: A review.

          Zeolites are crystalline, hydrated aluminosilicates of alkali earth cations, consisting of 3D frameworks of [SiO4]4- and [AlO4]5- tetrahedral, linked through the shared oxygen atoms, which have been widely applied in multifarious technological approaches such as adsorbents, catalysts, ion exchangers, molecular sieves for separation, and sorting the molecules according to their crystalline size dimensions. On the other hand, the unique and outstanding physical and chemical properties of zeolite materials such as porous character, ion exchangeability, water absorption capacity, immunomodulatory and antioxidative effects, biocompatibility and long-term chemical and biological stability, make them increasingly useful in various filed of biomedicine including drug delivery systems, wound healing, scaffolds used in tissue engineering, anti-bacterial and anti-microbial, implant coating, contrast agents, harmful ions removal from the body, gas absorber, hemodialysis, and teeth root filling. Therefore, this review focuses on the more recent advances of the use of zeolites in various biomedical applications feedbacks especially drug delivery, regenerative medicine, and tissue engineering with special emphasis on their biomaterial perspectives.
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            Polyurethane film prepared from ball-milled algal polyol particle and activated carbon filler for NH 3 –N removal

            This research offers a novel approach of free chemical preparation to obtain algae-based biopolyol through a ball milling method. The algae-based polyurethane (AlgPU) film was obtained from a casting solution made of ball-milled algal polyol particle and methylene diphenyl diisocyanate (MDI). The characteristics of the material had been investigated using Fourier Transform Infrared, Scanning Electron Microscopy – Electron Dispersive Spectroscopy, Differential Scanning Calorimetry, and Tensile Strength Analysis. The surface area was determined by Brunauer–Emmett–Teller (BET) isotherm, meanwhile the total pore volume was by Barrett-Joyner-Halenda (BJH) isotherm, based on the adsorption-desorption of N2. The addition of activated carbon contributed in the increase of functional group and surface area, which were important for the NH3–N removal. As a result, the adsorption capacity increased greatly after the addition of activated carbon (from 187.84 to 393.43 μg/g). The results also suggested AlgPU as a good matrix for immobilizing activated carbon filler. The adsorption shows a better fit with Langmuir isotherm model, with R2 = 0.97487 and root-mean-square error (RMSE) = 33.91952, compared to Freundlich isotherm model (R2 = 0.96477 and RMSE = 44.05388). This means the NH3–N adsorption followed the assumption of homogenous and monolayer adsorption, in which the maximum adsorption was found to be 797.95 μg/g. This research suggests the potential of newly developed material for NH3–N removal.
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              Atonic Postpartum Hemorrhage: Blood Loss, Risk Factors, and Third Stage Management

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                Author and article information

                Journal
                Narra J
                Narra J
                NarraJ
                Narra J
                Narra Sains Indonesia
                2807-2618
                August 2024
                18 July 2024
                : 4
                : 2
                : e835
                Affiliations
                [1 ]Graduate School of Mathematics and Applied Sciences , Universitas Syiah Kuala, Banda Aceh, Indonesia
                [2 ]Department of Midwifery , Health Polytechnic of Aceh Ministry of Health, Aceh Besar, Indonesia
                [3 ]Laboratory of Reproduction , Faculty of Veterinary Medicine, Universitas Syiah Kuala, Banda Aceh, Indonesia
                [4 ]Department of Chemistry Education , Faculty of Teacher Training and Education, Universitas Syiah Kuala, Banda Aceh, Indonesia
                [5 ]Department of Obstetrics and Gynecology , Faculty of Medicine, Universitas Syiah Kuala, Banda Aceh, Indonesia
                [6 ]Aquaculture Program , Faculty of Fisheries and Marine Science, Universitas Teuku Umar, Aceh Barat, Indonesia
                Author notes
                [* ]Corresponding author: adlim@ 123456usk.ac.id
                Article
                NarraJ-4-e835
                10.52225/narra.v4i2.835
                11392008
                5a661d6f-e4c3-45fb-92f7-49f62958c2d8
                © 2024 The Author(s).

                This is an Open Access article distributed under the terms of the Creative Commons Attribution Licence (CC BY NC 4.0), which permits copying, adaptation and redistribution, provided the original work is properly cited ( https://creativecommons.org/licenses/by-nc/4.0/).

                History
                : 3 May 2024
                : 8 July 2024
                Page count
                Pages: 8
                Categories
                Short Communication

                natural zeolite,super absorbent polymer,sap,maternity,labor
                natural zeolite, super absorbent polymer, sap, maternity, labor

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