A case of acute necrotizing pancreatitis due to Mycoplasma pneumoniae infection was
treated in an 8-year-old girl. She experienced acute pancreatitis during treatment
for M. pneumoniae. Contrast-enhanced computed tomographic scan revealed necrotizing
pancreatitis. The computed tomographic severity index was 8 points (grade E). A protease
inhibitor, ulinastatin, was provided via intravenous infusion but was ineffective.
Continuous regional arterial infusion therapy was provided with gabexate mesilate
(FOY-007, a protease inhibitor) and meropenem trihydrate, and the pancreatitis improved.
This case suggests that infusion therapy is safe and useful in treating necrotizing
pancreatitis in children.