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      Atrial Natriuretic Peptide and Arginine Vasopressin in Pregnancy and Pregnancy-Induced Hypertension

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          Abstract

          Atrial natriuretic peptide (ANP) and arginine vasopressin concentrations were measured in 9 patients with pregnancy-induced hypertension. The results were compared to those found in 7 normal pregnant women matched for age, duration of pregnancy, and parity. Plasma ANP levels were significantly higher in the pregnancy-induced hypertension patients than in the control group. Plasma arginine vasopressin concentrations, however, were not significantly different in the two populations. The mechanism of the observed rise in ANP concentrations in the patients with pregnancy-induced hypertension is not known. However, it may be related to a rise in intra-atrial pressures secondary to hypertension, an increase in baroreceptor discharge as a result of hypertension, or, less likely, the ANP may be released from extracardiac sites.

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          Author and article information

          Journal
          NEF
          Nephron
          10.1159/issn.1660-8151
          Nephron
          S. Karger AG
          1660-8151
          2235-3186
          1988
          1988
          09 December 2008
          : 49
          : 2
          : 140-143
          Affiliations
          aDepartment of Medicine, University of California at Irvine, Calif.; bNichols Institute, San Juan Capistrano, Calif., USA
          Article
          185040 Nephron 1988;49:140–143
          10.1159/000185040
          2967920
          © 1988 S. Karger AG, Basel

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          Page count
          Pages: 4
          Categories
          Original Paper

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