Pritesh Krishnakumar: Role: ConceptualizationRole: InvestigationRole: MethodologyRole: Writing – original
draftRole: Writing – review & editing
Stephan Riemer: Role: ConceptualizationRole: InvestigationRole: MethodologyRole: Writing – original
draft
Roshan Perera:
ORCID: http://orcid.org/0000-0001-7239-7404
Role: InvestigationRole: MethodologyRole: Writing – review & editing
Thomas Lingner: Role: Data curationRole: MethodologyRole: Writing – review & editing
Alexander Goloborodko: Role: InvestigationRole: MethodologyRole: Writing – review & editing
Hazem Khalifa:
ORCID: http://orcid.org/0000-0002-4621-4624
Role: InvestigationRole: Writing – review & editing
Franck Bontems: Role: ConceptualizationRole: InvestigationRole: Writing – review & editing
Felix Kaufholz:
ORCID: http://orcid.org/0000-0002-1402-2628
Role: InvestigationRole: MethodologyRole: Writing – review & editing
Mohamed A. El-Brolosy:
ORCID: http://orcid.org/0000-0003-2433-1851
Role: InvestigationRole: Writing – review & editing
Roland Dosch:
ORCID: http://orcid.org/0000-0001-9247-8586
Role: Funding acquisitionRole: Project administrationRole: ResourcesRole: Writing
– original draftRole: Writing – review & editing
Cecilia Moens: Role: Editor
Journal ID (nlm-ta): PLoS Genet
Journal ID (iso-abbrev): PLoS Genet
Journal ID (publisher-id): plos
Journal ID (pmc): plosgen
Title:
PLoS Genetics
Publisher:
Public Library of Science
(San Francisco, CA USA
)
ISSN
(Print):
1553-7390
ISSN
(Electronic):
1553-7404
Publication date
(Electronic):
6
November
2018
Publication date Collection:
November
2018
Volume: 14
Issue: 11
Electronic Location Identifier: e1007696
Affiliations
[1
]
Institute for Developmental Biochemistry, University Medical Center, Göttingen, Germany
[2
]
Laboratory of Metabolism, Department of Internal Medicine Specialties, Faculty of
Medicine, University of Geneva, Switzerland
[3
]
Institute of Human Genetics, University Medical Center, Göttingen, Germany
Fred Hutchinson Cancer Research Center, UNITED STATES
Author notes
The authors have declared that no competing interests exist.
Author information
Article
Publisher ID:
PGENETICS-D-18-00493
DOI: 10.1371/journal.pgen.1007696
PMC ID: 6219760
PubMed ID: 30399145
SO-VID: 5b37e4a9-040e-4768-b090-0767f0d609a6
Copyright © © 2018 Krishnakumar et al
License:
This is an open access article distributed under the terms of the
Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided
the original author and source are credited.
Funded by: German Egyptian Research Long-term Scholarship
Award ID: 91664584
Award Recipient
:
ORCID: http://orcid.org/0000-0002-4621-4624
Hazem Khalifa
Funded by: funder-id http://dx.doi.org/10.13039/501100001659, Deutsche Forschungsgemeinschaft;
Award ID: DO 740/2-3
Award Recipient
:
ORCID: http://orcid.org/0000-0001-9247-8586
Roland Dosch
Funded by: funder-id http://dx.doi.org/10.13039/501100001650, German Academic Exchange Service New Delhi;
Award Recipient
:
Pritesh Krishnakumar
Funded by: funder-id http://dx.doi.org/10.13039/501100001650, German Academic Exchange Service New Delhi;
Award Recipient
:
ORCID: http://orcid.org/0000-0001-7239-7404
Roshan Perera
This work was supported by a GZMB stipend, a GGNB bridging fund (SR), the German Academic
Exchange Service, DAAD
https://www.daad.de/en/) (PK, RP, HK), the Deutsche Forschungsgemeinschaft (DO 740/2-3) (
http://www.dfg.de) the GGNB Junior Group Stipend and the ‘‘Forschungsförderungsprogramm’’ of the University
Medical Center Göttingen (RD). The funders had no role in study design, data collection
and analysis, decision to publish, or preparation of the manuscript.
Subject:
Research Article
Subject:
Research and Analysis Methods
Subject:
Animal Studies
Subject:
Experimental Organism Systems
Subject:
Model Organisms
Subject:
Zebrafish
Subject:
Research and Analysis Methods
Subject:
Model Organisms
Subject:
Zebrafish
Subject:
Research and Analysis Methods
Subject:
Animal Studies
Subject:
Experimental Organism Systems
Subject:
Animal Models
Subject:
Zebrafish
Subject:
Biology and Life Sciences
Subject:
Organisms
Subject:
Eukaryota
Subject:
Animals
Subject:
Vertebrates
Subject:
Fish
Subject:
Osteichthyes
Subject:
Zebrafish
Subject:
Biology and Life Sciences
Subject:
Developmental Biology
Subject:
Embryology
Subject:
Embryos
Subject:
Research and Analysis Methods
Subject:
Database and Informatics Methods
Subject:
Bioinformatics
Subject:
Sequence Analysis
Subject:
Sequence Motif Analysis
Subject:
Biology and Life Sciences
Subject:
Cell Biology
Subject:
Cellular Types
Subject:
Animal Cells
Subject:
Germ Cells
Subject:
Research and Analysis Methods
Subject:
Database and Informatics Methods
Subject:
Bioinformatics
Subject:
Sequence Analysis
Subject:
Sequence Alignment
Subject:
Research and Analysis Methods
Subject:
Animal Studies
Subject:
Experimental Organism Systems
Subject:
Model Organisms
Subject:
Drosophila Melanogaster
Subject:
Research and Analysis Methods
Subject:
Model Organisms
Subject:
Drosophila Melanogaster
Subject:
Research and Analysis Methods
Subject:
Animal Studies
Subject:
Experimental Organism Systems
Subject:
Animal Models
Subject:
Drosophila Melanogaster
Subject:
Biology and Life Sciences
Subject:
Organisms
Subject:
Eukaryota
Subject:
Animals
Subject:
Invertebrates
Subject:
Arthropoda
Subject:
Insects
Subject:
Drosophila
Subject:
Drosophila Melanogaster
Subject:
Biology and Life Sciences
Subject:
Biochemistry
Subject:
Proteins
Subject:
Intrinsically Disordered Proteins
Subject:
Research and Analysis Methods
Subject:
Animal Studies
Subject:
Experimental Organism Systems
Subject:
Model Organisms
Subject:
Xenopus
Subject:
Research and Analysis Methods
Subject:
Model Organisms
Subject:
Xenopus
Subject:
Research and Analysis Methods
Subject:
Animal Studies
Subject:
Experimental Organism Systems
Subject:
Animal Models
Subject:
Xenopus
Subject:
Biology and Life Sciences
Subject:
Organisms
Subject:
Eukaryota
Subject:
Animals
Subject:
Vertebrates
Subject:
Amphibians
Subject:
Frogs
Subject:
Xenopus