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      A realist review of interventions and strategies to promote evidence-informed healthcare: a focus on change agency

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          Abstract

          Background

          Change agency in its various forms is one intervention aimed at improving the effectiveness of the uptake of evidence. Facilitators, knowledge brokers and opinion leaders are examples of change agency strategies used to promote knowledge utilization. This review adopts a realist approach and addresses the following question: What change agency characteristics work, for whom do they work, in what circumstances and why?

          Methods

          The literature reviewed spanned the period 1997-2007. Change agency was operationalized as roles that are aimed at effecting successful change in individuals and organizations. A theoretical framework, developed through stakeholder consultation formed the basis for a search for relevant literature. Team members, working in sub groups, independently themed the data and developed chains of inference to form a series of hypotheses regarding change agency and the role of change agency in knowledge use.

          Results

          24, 478 electronic references were initially returned from search strategies. Preliminary screening of the article titles reduced the list of potentially relevant papers to 196. A review of full document versions of potentially relevant papers resulted in a final list of 52 papers. The findings add to the knowledge of change agency as they raise issues pertaining to how change agents’ function, how individual change agent characteristics effect evidence-informed health care, the influence of interaction between the change agent and the setting and the overall effect of change agency on knowledge utilization. Particular issues are raised such as how accessibility of the change agent, their cultural compatibility and their attitude mediate overall effectiveness. Findings also indicate the importance of promoting reflection on practice and role modeling. The findings of this study are limited by the complexity and diversity of the change agency literature, poor indexing of literature and a lack of theory-driven approaches.

          Conclusion

          This is the first realist review of change agency. Though effectiveness evidence is weak, change agent roles are evolving, as is the literature, which requires more detailed description of interventions, outcomes measures, the context, intensity, and levels at which interventions are implemented in order to understand how change agent interventions effect evidence-informed health care.

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          Most cited references44

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          The Many Meanings of Research Utilization

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            Translating guidelines into practice. A systematic review of theoretic concepts, practical experience and research evidence in the adoption of clinical practice guidelines.

            To recommend effective strategies for implementing clinical practice guidelines (CPGs). The Research and Development Resource Base in Continuing Medical Education, maintained by the University of Toronto, was searched, as was MEDLINE from January 1990 to June 1996, inclusive, with the use of the MeSH heading "practice guidelines" and relevant text words. Studies of CPG implementation strategies and reviews of such studies were selected. Randomized controlled trials and trials that objectively measured physicians' performance or health care outcomes were emphasized. Articles were reviewed to determine the effect of various factors on the adoption of guidelines. The articles showed that CPG dissemination or implementation processes have mixed results. Variables that affect the adoption of guidelines include qualities of the guidelines, characteristics of the health care professional, characteristics of the practice setting, incentives, regulation and patient factors. Specific strategies fell into 2 categories: primary strategies involving mailing or publication of the actual guidelines and secondary interventional strategies to reinforce the guidelines. The interventions were shown to be weak (didactic, traditional continuing medical education and mailings), moderately effective (audit and feedback, especially concurrent, targeted to specific providers and delivered by peers or opinion leaders) and relatively strong (reminder systems, academic detailing and multiple interventions). The evidence shows serious deficiencies in the adoption of CPGs in practice. Future implementation strategies must overcome this failure through an understanding of the forces and variables influencing practice and through the use of methods that are practice- and community-based rather than didactic.
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              Role of "external facilitation" in implementation of research findings: a qualitative evaluation of facilitation experiences in the Veterans Health Administration

              Background Facilitation has been identified in the literature as a potentially key component of successful implementation. It has not, however, either been well-defined or well-studied. Significant questions remain about the operational definition of facilitation and about the relationship of facilitation to other interventions, especially to other change agent roles when used in multi-faceted implementation projects. Researchers who are part of the Quality Enhancement Research Initiative (QUERI) are actively exploring various approaches and processes, including facilitation, to enable implementation of best practices in the Veterans Health Administration health care system – the largest integrated healthcare system in the United States. This paper describes a systematic, retrospective evaluation of implementation-related facilitation experiences within QUERI, a quality improvement program developed by the US Department of Veterans Affairs. Methods A post-hoc evaluation was conducted through a series of semi-structured interviews to examine the concept of facilitation across several multi-site QUERI implementation studies. The interview process is based on a technique developed in the field of education, which systematically enhances learning through experience by stimulating recall and reflection regarding past complex activities. An iterative content analysis approach relative to a set of conceptually-based interview questions was used for data analysis. Findings Findings suggest that facilitation, within an implementation study initiated by a central change agency, is a deliberate and valued process of interactive problem solving and support that occurs in the context of a recognized need for improvement and a supportive interpersonal relationship. Facilitation was described primarily as a distinct role with a number of potentially crucial behaviors and activities. Data further suggest that external facilitators were likely to use or integrate other implementation interventions, while performing this problem-solving and supportive role. Preliminary Conclusions This evaluation provides evidence to suggest that facilitation could be considered a distinct implementation intervention, just as audit and feedback, educational outreach, or similar methods are considered to be discrete interventions. As such, facilitation should be well-defined and explicitly evaluated for its perceived usefulness within multi-intervention implementation projects. Additionally, researchers should better define the specific contribution of facilitation to the success of implementation in different types of projects, different types of sites, and with evidence and innovations of varying levels of strength and complexity.
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                Author and article information

                Contributors
                Journal
                Implement Sci
                Implement Sci
                Implementation Science : IS
                BioMed Central
                1748-5908
                2013
                8 September 2013
                : 8
                : 107
                Affiliations
                [1 ]Institute of Nursing and Health Research/School of Nursing, University of Ulster, Shore Road, Newtownabbey, BT37 0QB, Antrim, Co, Northern Ireland
                [2 ]School of Healthcare Sciences, Bangor University, Fron Heulog, Ffriddoedd Road, Bangor, UK
                [3 ]School of Nursing, McMaster University, 1280 Main St W, Ontario, Hamilton, Canada
                [4 ]School of Nursing and Midwifery, Deakin University, 221 Burwood Hwy, Victoria 3125, Burwood, Australia
                [5 ]Deakin-Southern Health Nursing Research Centre, I Block 246 Clayton Road, Victoria 3168, Clayton, Australia
                [6 ]Alfred-Deakin Centre for Nursing Research, The Alfred Hospital, 55 Commercial Rd, Victoria 3004, Melbourne, Australia
                [7 ]School of Nursing and Midwifery, University of Plymouth, Drake Circus, PL4 8AA, Plymouth, UK
                [8 ]Alyce A Schultz, Independent Consultant, 3172 Hillcrest Drive 59715, Bozeman, MT, USA
                [9 ]School of Nursing, Dalhousie University, Nova Scotia B3H 4R2, Halifax, Canada
                [10 ]EBP/Evaluation Consultant, 321 Middle Street Amherst, Massachusetts, & Health Services Department, Boston University School of Public Health, Boston, Massachusetts, USA
                [11 ]School of Nursing, University of Michigan, 400 North Ingalls Building, Michigan 48109–5482, Ann Arbor, MI, USA
                [12 ]Department of Neurobiology, Care Sciences and Society, Division of Nursing, Karolinska Institutet, Sweden
                [13 ]Faculty of Nursing, Midwifery and Health, University of Technology Sydney, Building 10, 235-253 Jones Street, Ultimo, Australia
                Article
                1748-5908-8-107
                10.1186/1748-5908-8-107
                3848622
                24010732
                5bc8a697-1faf-48df-abfc-179af83ddcbe
                Copyright © 2013 mccormack et al.; licensee BioMed Central Ltd.

                This is an Open Access article distributed under the terms of the Creative Commons Attribution License ( http://creativecommons.org/licenses/by/2.0), which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.

                History
                : 13 January 2013
                : 29 August 2013
                Categories
                Research

                Medicine
                realist synthesis,evidence-informed health care,change agency,facilitators,opinion leaders,knowledge brokers’ knowledge utilization

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