Blog
About

0
views
0
recommends
+1 Recommend
0 collections
    0
    shares
      • Record: found
      • Abstract: found
      • Article: not found

      The effects of corticosteroids on behavior in children with nephrotic syndrome.

      Pediatric Nephrology (Berlin, Germany)

      Psychiatric Status Rating Scales, psychology, drug therapy, complications, Nephrotic Syndrome, Male, Humans, epidemiology, Great Britain, Female, Child, Preschool, chemically induced, Child Behavior Disorders, Child, Attention, Aggression, therapeutic use, adverse effects, Adrenal Cortex Hormones

      Read this article at

      ScienceOpenPublisherPubMed
      Bookmark
          There is no author summary for this article yet. Authors can add summaries to their articles on ScienceOpen to make them more accessible to a non-specialist audience.

          Abstract

          The objective of this study was to measure the frequency and severity of the behavioral effects of high-dose oral steroid therapy in children with nephrotic syndrome. We conducted a prospective assessment of the behavior of 12 children using a standardized psychological questionnaire at the time of diagnosis and again after 4 weeks of steroid therapy. A group of control children was also assessed. There was a significant increase in the total behavior score ( P=0.03) and specifically in aggressive and poor attention behavior items in the group of nephrotic children compared with the control group. Four of the children with nephrotic syndrome developed abnormal behavior in the clinical range compared with none of the controls. In conclusion, children with nephrotic syndrome treated with high-dose oral steroids are at risk of developing clinically relevant behavioral changes.

          Related collections

          Author and article information

          Journal
          10.1007/s00467-003-1295-x
          14577022

          Comments

          Comment on this article