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      Immunoreactive Parathyroid Hormone and Calcitonin in Children’s Cerebrospinal Fluid

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          Abstract

          Cerebrospinal fluid (CSF) levels of immunoreactive parathyroid hormone (iPTH) and immunoreactive calcitonin (iCT) were measured by radioimmunoassay in 23 outpatient leukemic children on maintenance chemotherapy. These hormones were detectable in the CSF of all patients: iPTH 148 ± 11 pg/ml (mean ± SEM); iCT 14.3 ± 0.8 pg/ml. iPTH and iCT were also measured in serum (iPTH 396 ± 18 pg/ml; iCT 32.3 ± 1.4 pg/ml). CSF values were significantly lower (p < 0.001) than serum concentrations; no significant correlation between the two compartments was found. Our study indicates the presence of iPTH and iCT in the CSF of children.

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          Author and article information

          Journal
          HRE
          Horm Res Paediatr
          10.1159/issn.1663-2818
          Hormone Research in Paediatrics
          S. Karger AG
          1663-2818
          1663-2826
          1986
          1986
          28 November 2008
          : 23
          : 3
          : 177-180
          Affiliations
          Department of Pediatrics, University of Pisa, Italy
          Article
          180319 Horm Res 1986;23:177–180
          10.1159/000180319
          3949289
          © 1986 S. Karger AG, Basel

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          Pages: 4
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