Effect of Cannabidiol on Drop Seizures in the Lennox–Gastaut Syndrome

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Abstract

<p class="first" id="d1313982e137">Cannabidiol has been used for treatment-resistant seizures in patients with severe early-onset epilepsy. We investigated the efficacy and safety of cannabidiol added to a regimen of conventional antiepileptic medication to treat drop seizures in patients with the Lennox-Gastaut syndrome, a severe developmental epileptic encephalopathy. </p>

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Journal

Title: New England Journal of Medicine

Abbreviated Title: N Engl J Med

Publisher: Massachusetts Medical Society

ISSN (Print): 0028-4793

ISSN (Electronic): 1533-4406

Publication date Created: May 17 2018

Publication date (Print): May 17 2018

Volume: 378

Issue: 20

Pages: 1888-1897

Affiliations

[1 ]From New York University Langone Comprehensive Epilepsy Center, New York (O.D.); Nationwide Children’s Hospital and the Ohio State University College of Medicine, Columbus (A.D.P.), and the University of Cincinnati Medical Center, Department of Neurology, Cincinnati (M.P.) — all in Ohio; UCL Great Ormond Street Institute of Child Health, London (J.H.C.), GW Research Ltd., Cambridge (S.M.G., C.R., D.C.), and the Royal Hospital for Children and School of Medicine, University of Glasgow, Glasgow (S.M.Z.) —...

Article

DOI: 10.1056/NEJMoa1714631

PubMed ID: 29768152

SO-VID: 5c311844-9c6b-463d-aa3d-c5a56a9f5e76

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