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      The worldwide Protein Data Bank (wwPDB): ensuring a single, uniform archive of PDB data

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          Abstract

          The worldwide Protein Data Bank (wwPDB) is the international collaboration that manages the deposition, processing and distribution of the PDB archive. The online PDB archive is a repository for the coordinates and related information for more than 38 000 structures, including proteins, nucleic acids and large macromolecular complexes that have been determined using X-ray crystallography, NMR and electron microscopy techniques. The founding members of the wwPDB are RCSB PDB (USA), MSD-EBI (Europe) and PDBj (Japan) [H.M. Berman, K. Henrick and H. Nakamura (2003) Nature Struct. Biol., 10, 980]. The BMRB group (USA) joined the wwPDB in 2006. The mission of the wwPDB is to maintain a single archive of macromolecular structural data that are freely and publicly available to the global community. Additionally, the wwPDB provides a variety of services to a broad community of users. The wwPDB website at http://www.wwpdb.org/ provides information about services provided by the individual member organizations and about projects undertaken by the wwPDB.

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          Most cited references19

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          The RCSB PDB information portal for structural genomics

          The RCSB Protein Data Bank (PDB) offers online tools, summary reports and target information related to the worldwide structural genomics initiatives from its portal at . There are currently three components to this site: Structural Genomics Initiatives contains information and links on each structural genomics site, including progress reports, target lists, target status, targets in the PDB and level of sequence redundancy; Targets provides combined target information, protocols and other data associated with protein structure determination; and Structures offers an assessment of the progress of structural genomics based on the functional coverage of the human genome by PDB structures, structural genomics targets and homology models. Functional coverage can be examined according to enzyme classification, gene ontology (biological process, cell component and molecular function) and disease.
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            PQS: a protein quaternary structure file server.

            K Henrick (1998)
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              The RCSB Protein Data Bank: a redesigned query system and relational database based on the mmCIF schema

              The Protein Data Bank (PDB) is the central worldwide repository for three-dimensional (3D) structure data of biological macromolecules. The Research Collaboratory for Structural Bioinformatics (RCSB) has completely redesigned its resource for the distribution and query of 3D structure data. The re-engineered site is currently in public beta test at http://pdbbeta.rcsb.org. The new site expands the functionality of the existing site by providing structure data in greater detail and uniformity, improved query and enhanced analysis tools. A new key feature is the integration and searchability of data from over 20 other sources covering genomic, proteomic and disease relationships. The current capabilities of the re-engineered site, which will become the RCSB production site at http://www.pdb.org in late 2005, are described.
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                Author and article information

                Journal
                Nucleic Acids Res
                Nucleic Acids Res
                nar
                Nucleic Acids Research
                Nucleic Acids Research
                Oxford University Press
                0305-1048
                1362-4962
                January 2007
                16 November 2006
                16 November 2006
                : 35
                : Database issue
                : D301-D303
                Affiliations
                RCSB Protein Data Bank, Department of Chemistry and Chemical Biology, Rutgers, The State University of New Jersey 610 Taylor Road, Piscataway, NJ 08854-8087, USA
                1MSD-EBI, EMBL Outstation-Hinxton Cambridge CB10 1SD, UK
                2PDBj, Institute for Protein Research, Osaka University, 3-2 Yamadaoka Suita, Osaka 565-0871, Japan
                3BioMagResBank, University of Wisconsin-Madison, Department of Biochemistry, 433 Babcock Drive, Madison WI 53706, USA
                Author notes
                *To whom correspondence should be addressed. Tel: +1 732 445 4667; Fax: +1 732 445 4320; Email: berman@ 123456rcsb.rutgers.edu
                Article
                10.1093/nar/gkl971
                1669775
                17142228
                5c6bdb57-bc47-4500-930d-d05b85b8aa13
                © 2006 The Author(s)

                This is an Open Access article distributed under the terms of the Creative Commons Attribution Non-Commercial License ( http://creativecommons.org/licenses/by-nc/2.0/uk/) which permits unrestricted non-commercial use, distribution, and reproduction in any medium, provided the original work is properly cited.

                History
                : 14 September 2006
                : 20 October 2006
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                Genetics
                Genetics

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