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      An evaluation of a novel dual treponemal/nontreponemal point-of-care test for syphilis as a tool to distinguish active from past treated infection.

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          Abstract

          Most syphilis point-of-care (POC) tests detect treponemal antibodies, which persist after successful treatment. Subsequent POC tests are positive, despite no active infection, and can lead to unnecessary treatment. We evaluated a new POC test, incorporating a nontreponemal component, to distinguish active from past infection.

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          Author and article information

          Journal
          Clin. Infect. Dis.
          Clinical infectious diseases : an official publication of the Infectious Diseases Society of America
          Oxford University Press (OUP)
          1537-6591
          1058-4838
          Jul 15 2015
          : 61
          : 2
          Affiliations
          [1 ] Kirby Institute, University of New South Wales, Sydney.
          [2 ] Victorian Infectious Diseases Reference Laboratory, Melbourne.
          [3 ] Melbourne Sexual Health Centre, Carlton.
          [4 ] Burnet Institute, Melbourne.
          [5 ] SEALS Laboratory, Prince of Wales Hospital, Randwick.
          [6 ] Sydney Sexual Health Centre.
          [7 ] Central Clinical School, Monash University, Melbourne, Australia.
          Article
          civ243
          10.1093/cid/civ243
          25810288
          5c7c3b75-f2fe-4b49-aa4e-2a7b60095cfe
          History

          diagnosis,point-of-care test,syphilis
          diagnosis, point-of-care test, syphilis

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