0
views
0
recommends
+1 Recommend
0 collections
    0
    shares
      • Record: found
      • Abstract: found
      • Article: not found

      Byakangelicin induces cytochrome P450 3A4 expression via transactivation of pregnane X receptors in human hepatocytes.

      Read this article at

      ScienceOpenPublisherPMC
      Bookmark
          There is no author summary for this article yet. Authors can add summaries to their articles on ScienceOpen to make them more accessible to a non-specialist audience.

          Abstract

          Byakangelicin is found in extracts of the root of Angelica dahurica, used in Korea and China as a traditional medicine to treat colds, headache and toothache. As byakangelicin can inhibit the effects of sex hormones, it may increase the catabolism of endogenous hormones. Therefore, this study investigated the effects of byakangelicin on the cytochrome P450 isoform cytochrome (CY) P3A4 in human hepatocytes.

          Related collections

          Author and article information

          Journal
          Br. J. Pharmacol.
          British journal of pharmacology
          Wiley
          1476-5381
          0007-1188
          Jan 2011
          : 162
          : 2
          Affiliations
          [1 ] Department of Pharmacology, Nanjing Medical University, Jiangsu, China. jianyang@njmu.edu.cn
          Article
          10.1111/j.1476-5381.2010.01069.x
          3031064
          20942813
          5c8f4c53-a95b-4bec-8b0b-5af1ce80c71f
          History

          Comments

          Comment on this article