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      Patterns of Spontaneous Cortisol and Growth Hormone Secretion in Rhesus Monkeys During the Sleep-Waking Cycle

      , , ,

      Neuroendocrinology

      S. Karger AG

      Cortisol, Growth hormone, Sleep, EEG, Episodic secretion

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          Abstract

          Plasma concentrations of cortisol (F) and growthhormone were determined in samples obtained sequentially at 15 min intervals for 12 h night and 12 h day sessions in juvenile male monkeys (6–9.5 lb.) implanted with right atrial catheters. Electroencephalographic (EEG), electrooculographic (EOG), and electromyographic (EMG) activity were recorded. Cortisol was secreted episodically, increasing in frequency and concentration during the latter portion of the night and early morning hours. Growth hormone was also secreted episodically but bore no apparent relationship to either sleep stage or time of day.

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          Author and article information

          Journal
          NEN
          Neuroendocrinology
          10.1159/issn.0028-3835
          Neuroendocrinology
          S. Karger AG
          0028-3835
          1423-0194
          1974
          1974
          20 March 2008
          : 14
          : 3-4
          : 165-173
          Affiliations
          Department of Pharmacology, Albert Einstein College of Medicine, and Department of Neurology, Montefiore Hospital and Medical Center, Bronx, N.Y.
          Article
          122256 Neuroendocrinology 1974;14:165–173
          10.1159/000122256
          4368996
          © 1974 S. Karger AG, Basel

          Copyright: All rights reserved. No part of this publication may be translated into other languages, reproduced or utilized in any form or by any means, electronic or mechanical, including photocopying, recording, microcopying, or by any information storage and retrieval system, without permission in writing from the publisher. Drug Dosage: The authors and the publisher have exerted every effort to ensure that drug selection and dosage set forth in this text are in accord with current recommendations and practice at the time of publication. However, in view of ongoing research, changes in government regulations, and the constant flow of information relating to drug therapy and drug reactions, the reader is urged to check the package insert for each drug for any changes in indications and dosage and for added warnings and precautions. This is particularly important when the recommended agent is a new and/or infrequently employed drug. Disclaimer: The statements, opinions and data contained in this publication are solely those of the individual authors and contributors and not of the publishers and the editor(s). The appearance of advertisements or/and product references in the publication is not a warranty, endorsement, or approval of the products or services advertised or of their effectiveness, quality or safety. The publisher and the editor(s) disclaim responsibility for any injury to persons or property resulting from any ideas, methods, instructions or products referred to in the content or advertisements.

          Page count
          Pages: 9
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