16
views
0
recommends
+1 Recommend
1 collections
    0
    shares

      Call for Papers: Epidemiology of CKD and its Complications

      Submit here by August 31, 2024

      About Kidney and Blood Pressure Research: 2.3 Impact Factor I 4.8 CiteScore I 0.674 Scimago Journal & Country Rank (SJR)

      • Record: found
      • Abstract: found
      • Article: found

      Intravenous Catheter for Intracorporeal Plasma Filtration

      research-article

      Read this article at

      ScienceOpenPublisherPubMed
      Bookmark
          There is no author summary for this article yet. Authors can add summaries to their articles on ScienceOpen to make them more accessible to a non-specialist audience.

          Abstract

          Future advances in dialysis of end-stage renal disease patients may include improvements in therapeutic continuity and patient mobility. Continuous renal replacement therapies could lead to self-contained, mobile and potentially wearable dialysis units. We investigated an experimental, intravenous slow-continuous plasma separation system (IPSS) as a precursor to direct intravenous hemofiltration. An intracorporeal catheter employs asymmetric hollow fibers to separate blood cells from plasma in vivo. The fibers possess a sieving coefficient of 0.7 µm and remove 99.99% of all platelets. In vivo, catheters sustain an average plasma separation flow rate of 3 ml/min over 22 h, sufficient to remove 2 net liters of water from pigs through an extracorporeal hemofilter. Used catheter fibers are relatively free of protein deposition or clots in situ. In vitro studies suggest that human catheters may perform at 3–4 times the rate of porcine catheters. IPSS is proposed for acute fluid removal in CHF patients refractory to diuretics.

          Related collections

          Most cited references3

          • Record: found
          • Abstract: found
          • Article: found

          Interdialytic Weight Gain and Dry Weight

            Bookmark
            • Record: found
            • Abstract: found
            • Article: found

            Kt/V Is the Best Dialysis Dose Parameter

              Bookmark
              • Record: found
              • Abstract: found
              • Article: found

              Indications for Dialysis in the ICU: Renal Replacement vs. Renal Support

                Bookmark

                Author and article information

                Journal
                BPU
                Blood Purif
                10.1159/issn.0253-5068
                Blood Purification
                S. Karger AG
                978-3-8055-7372-6
                978-3-318-00813-5
                0253-5068
                1421-9735
                2002
                2002
                17 January 2002
                : 20
                : 1
                : 61-69
                Affiliations
                aTransvivo, Inc., Napa, Calif., USA, bRenal Research Institute, New York, N.Y., USA, and cDepartment of Nephrology, St. Bortolo Hospital, Vicenza, Italy
                Article
                46987 Blood Purif 2002;20:61–69
                10.1159/000046987
                11803161
                5cbb0df5-6869-4e02-a88b-279bc9f35364
                © 2002 S. Karger AG, Basel

                Copyright: All rights reserved. No part of this publication may be translated into other languages, reproduced or utilized in any form or by any means, electronic or mechanical, including photocopying, recording, microcopying, or by any information storage and retrieval system, without permission in writing from the publisher. Drug Dosage: The authors and the publisher have exerted every effort to ensure that drug selection and dosage set forth in this text are in accord with current recommendations and practice at the time of publication. However, in view of ongoing research, changes in government regulations, and the constant flow of information relating to drug therapy and drug reactions, the reader is urged to check the package insert for each drug for any changes in indications and dosage and for added warnings and precautions. This is particularly important when the recommended agent is a new and/or infrequently employed drug. Disclaimer: The statements, opinions and data contained in this publication are solely those of the individual authors and contributors and not of the publishers and the editor(s). The appearance of advertisements or/and product references in the publication is not a warranty, endorsement, or approval of the products or services advertised or of their effectiveness, quality or safety. The publisher and the editor(s) disclaim responsibility for any injury to persons or property resulting from any ideas, methods, instructions or products referred to in the content or advertisements.

                History
                Page count
                Figures: 8, References: 15, Pages: 9
                Categories
                Paper

                Cardiovascular Medicine,Nephrology
                Plasma separation,Experimental device,CHF,Fluid overload,Intravenous filtration catheter,Dialysis,Ultrafiltration

                Comments

                Comment on this article