Graphene oxide stabilized by PLA-PEG copolymers for the controlled delivery of paclitaxel.

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Abstract

To investigate the application of water-dispersible poly(lactide)-poly(ethylene glycol) (PLA-PEG) copolymers for the stabilization of graphene oxide (GO) aqueous dispersions and the feasibility of using the PLA-PEG stabilized GO as a delivery system for the potent anticancer agent paclitaxel.

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Journal ID (iso-abbrev): Eur J Pharm Biopharm

Title: European journal of pharmaceutics and biopharmaceutics : official journal of Arbeitsgemeinschaft fur Pharmazeutische Verfahrenstechnik e.V

Publisher: Elsevier BV

ISSN (Electronic): 1873-3441

ISSN (Print): 0939-6411

Publication date (Electronic): Jun 2015

Volume: 93

Affiliations

[1 ] Department of Pharmacy, Medical School, University of Patras, 26 500 Patras, Greece.

[2 ] Department of Materials Science and Engineering, University of Ioannina, 45110 Ioannina, Greece.

[3 ] Department of Pharmacy, Medical School, University of Patras, 26 500 Patras, Greece. Electronic address: avgoust@upatras.gr.

Article

Publisher Item ID: S0939-6411(15)00155-1

DOI: 10.1016/j.ejpb.2015.03.022

PubMed ID: 25817600

SO-VID: 5cd2922f-4df8-4e33-a840-8041c0d865da

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Keywords: Colloidal stability,Cytotoxicity,Graphene oxide,PLA–PEG,Paclitaxel

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Keywords: Colloidal stability, Cytotoxicity, Graphene oxide, PLA–PEG, Paclitaxel

Graphene oxide stabilized by PLA-PEG copolymers for the controlled delivery of paclitaxel.

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