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      Validation of a Simple Method for Assessing Sodium Intake in Dialysis Patients

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          Abstract

          It has been reported that sodium intake can be estimated in dialysis patients by the increment in the body sodium pool from the end of a dialysis session to the beginning of the following one. To verify the reliability of this method we compared the sodium intake, estimated by the interdialytic changes in plasma sodium concentration (C) and body water volume (V), to sodium removal during three consecutive sessions. For this purpose we investigated 9 nondiabetic patients, 5 females and 4 males, under chronic hemofiltration treatment. Sodium intake was estimated by the formula (C<sub>pre</sub> V<sub>pre</sub>) – (C<sub>post</sub> V<sub>post</sub>) using a flame photometer and electrical bioimpedance to determine the plasma sodium concentration and total body water, respectively. Sodium removal was calculated by the difference between sodium loss into the ultrafiltrate and sodium gain with the reinfusion fluid. The mean values of sodium intake calculated during the three intervals corresponded with the sodium losses measured during the three hemofiltration sessions in each patient (338 ± 55 vs. 329 ± 67 mEq; r = 0.92, p < 0.0001). A direct relationship was also observed between sodium intake and both interdialytic body weight increase (r = 0.89, p < 0.0001) and fluid loss during the sessions (r = 0.88, p < 0.0001). This data demonstrates that sodium intake can be properly estimated by the interdialytic changes in body water and plasma sodium concentrations. They also suggest that fluid intake may be influenced by sodium consumption and that sodium intake monitoring could be useful for the control of excessive interdialytic fluid gain.

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          Author and article information

          Journal
          BPU
          Blood Purif
          10.1159/issn.0253-5068
          Blood Purification
          S. Karger AG
          0253-5068
          1421-9735
          2001
          2001
          08 December 2000
          : 19
          : 1
          : 15-20
          Affiliations
          Servizio di Nefrologia e Dialisi, Ospedale Maggiore di Trieste, Italy
          Article
          14472 Blood Purif 2001;19:15–20
          10.1159/000014472
          11114572
          5cfb9f07-6328-42f7-a997-157fbe4f03bc
          © 2001 S. Karger AG, Basel

          Copyright: All rights reserved. No part of this publication may be translated into other languages, reproduced or utilized in any form or by any means, electronic or mechanical, including photocopying, recording, microcopying, or by any information storage and retrieval system, without permission in writing from the publisher. Drug Dosage: The authors and the publisher have exerted every effort to ensure that drug selection and dosage set forth in this text are in accord with current recommendations and practice at the time of publication. However, in view of ongoing research, changes in government regulations, and the constant flow of information relating to drug therapy and drug reactions, the reader is urged to check the package insert for each drug for any changes in indications and dosage and for added warnings and precautions. This is particularly important when the recommended agent is a new and/or infrequently employed drug. Disclaimer: The statements, opinions and data contained in this publication are solely those of the individual authors and contributors and not of the publishers and the editor(s). The appearance of advertisements or/and product references in the publication is not a warranty, endorsement, or approval of the products or services advertised or of their effectiveness, quality or safety. The publisher and the editor(s) disclaim responsibility for any injury to persons or property resulting from any ideas, methods, instructions or products referred to in the content or advertisements.

          History
          Page count
          Figures: 3, Tables: 2, References: 24, Pages: 6
          Categories
          Original Paper

          Cardiovascular Medicine,Nephrology
          Sodium intake,Body sodium pool,Hemodialysis,Sodium balance,Sodium,Sodium removal

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