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      Renal effects of long-term darbepoetin alpha treatment in hypertensive TGR(mRen2)27 rats.

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          Abstract

          Erytropoietin (EPO) has cytoprotective and angiogenic properties and has a beneficial effect in ischaemic conditions. Since the development of renal interstitial abnormalities are often associated with ischaemia, we studied the effects of the long-acting EPO analogue darbepoetin alpha (DA) on kidney damage in TGR(mRen2)27 (Ren2) rats.

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          Author and article information

          Journal
          J Renin Angiotensin Aldosterone Syst
          Journal of the renin-angiotensin-aldosterone system : JRAAS
          1752-8976
          1470-3203
          Jun 2012
          : 13
          : 2
          Affiliations
          [1 ] Department of Pathology and Medical Biology, University Medical Center Groningen and University of Groningen, Groningen, The Netherlands. a.s.frenay@umcg.nl
          Article
          1470320311432186
          10.1177/1470320311432186
          22282864

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