20
views
0
recommends
+1 Recommend
0 collections
    0
    shares
      • Record: found
      • Abstract: found
      • Article: not found

      Club drugs and Alcohol Abuse Predicted Drop-out and Poor Adherence among Methadone Maintenance Treatment Patients in Guangzhou, China

      research-article

      Read this article at

      ScienceOpenPublisherPMC
      Bookmark
          There is no author summary for this article yet. Authors can add summaries to their articles on ScienceOpen to make them more accessible to a non-specialist audience.

          Abstract

          Club drugs and alcohol abuse are prevalent among methadone maintenance treatment (MMT) patients. However, little is known about the association between these abuse and treatment outcomes among MMT patients. The aim of this study is to examine the prevalence of club drugs and alcohol abuse among MMT patientsand to investigate the associations between these abuse and treatment outcomes – drop-out and poor adherence. In this one-year cohort study conducting in Guangzhou, China, data including background characteristics, club drugs use in the last six months, alcohol use history and treatment-related information was collected. Cox regression analyses and log-binomial regression analyses were applied to identify the associations between these abuse and drop-out and poor adherence respectively. Thirty-seven participants (9.2%) admitted to the use of at least one type of club drugs in the last six months and eighty-eight (21.9%) were identified as alcohol abusers. Of all participants, 21.0% had dropped out of treatment and 27.7% exhibited poor adherence during the study period. Adjusting for significant background variables, use of at least one type of club drugs [hazards ratio (HR) = 1.90, 95% confidence Interval (CI) = 1.01–3.56] and use of methamphetamine in the last six months (HR = 2.26, 95%CI = 1.15–4.43) significantly predicted drop-out. Frequency of having six or more drinks on one drinking occasion when drinking [risk ratio (RR) = 1.87, 95% CI = 1.16–2.95] significantly predicted poor adherence. Our findings indicated that club drugs and alcohol abuse predicted drop-out and poor adherence among MMT patients. Early identification and intervention for the abuse should be taken into consideration when developing interventions tailored to improve treatment outcomes among MMT patients.

          Related collections

          Author and article information

          Journal
          8915313
          1056
          AIDS Care
          AIDS Care
          AIDS care
          0954-0121
          1360-0451
          24 April 2020
          30 November 2016
          April 2017
          22 May 2020
          : 29
          : 4
          : 458-463
          Affiliations
          [a ]Department of Medical Statistics and Epidemiology, School of Public Health, Sun Yat-sen University, Guangzhou, China;
          [b ]Sun Yat-sen Global Health Instistute, Institute of State Governance, Sun Yat-sen University, Guangzhou, China;
          [c ]Department of HIV/AIDS Prevention and Control, Guangzhou Center for Disease Prevention and Control, Guangzhou, China
          Author notes
          [* ] Corresponding author: Jing Gu, PhD, Associate Professor, Department of Medical Statistics and Epidemiology, School of Public Health, SunYat-senUniversity, Address: 309, School of Public Health, SunYat-senUniversity, No. 74 Zhongshan Road II, Guangzhou, Guangdong, China. 510080, gujing5@ 123456mail.sysu.edu.cn ; Office: 86-20-87335413; Fax: 86-20-87330446
          Article
          PMC7243263 PMC7243263 7243263 nihpa883663
          10.1080/09540121.2016.1259452
          7243263
          27903083
          5e2a60a8-ff56-47dd-9528-b606bb7b2132
          History
          Categories
          Article

          adherence,club drugs,drop-out,alcohol,Methadone maintenance treatment

          Comments

          Comment on this article