Recombinant factor VIII SQ--inactivation kinetics in aqueous solution and the influence of disaccharides and sugar alcohols.

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Abstract

To investigate the influence of various nonreducing disaccharides and sugar alcohols on the inactivation kinetics of recombinant factor VIII SQ (r-VIII SQ) in aqueous solution not containing albumin as a stabiliser.

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Journal

Journal ID (iso-abbrev): Pharm Res

Title: Pharmaceutical research

Publisher: Springer Science and Business Media LLC

ISSN: 0724-8741

ISSN (Print): 0724-8741

Publication date (Electronic): Dec 1997

Volume: 14

Issue: 12

Affiliations

[1 ] Department of Pharmaceutical Technology, Pharmacia & Upjohn AB, Stockholm, Sweden. angelica.fatouros@eu.pnu.com

Article

DOI: 10.1023/a:1012163309468

PubMed ID: 9453053

SO-VID: 5e3481e3-ff55-4ccf-9821-f87392456511

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