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      The Abandoned Trials of Pre-Exposure Prophylaxis for HIV: What Went Wrong?

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      PLoS Medicine
      Public Library of Science

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          Abstract

          The dramatic protests that shut down trials of tenofovir as pre-exposure prophylaxis against HIV may prove damaging in our fight against the HIV pandemic.

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          Most cited references9

          • Record: found
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          Trial of antiretroviral for HIV prevention on hold.

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            AIDS research. Cambodian leader throws novel prevention trial into limbo.

            Jon Cohen (2004)
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              • Article: not found

              Key AIDS study in Cambodia now in jeopardy

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                Author and article information

                Journal
                PLoS Med
                pbio
                PLoS Medicine
                Public Library of Science (San Francisco, USA )
                1549-1277
                1549-1676
                September 2005
                19 July 2005
                : 2
                : 9
                : e234
                Author notes

                Jerome A. Singh is at the Centre for the AIDS Programme of Research in South Africa and the Howard College School of Law, University of KwaZulu–Natal, Durban, South Africa, and the University of Toronto Joint Centre for Bioethics, Toronto, Ontario, Canada. Edward J. Mills is at the Centre for International Human Rights Law, University of Oxford, United Kingdom, and the Department of Clinical Epidemiology and Biostatistics, McMaster University, Hamilton, Ontario, Canada.

                Competing Interests: The authors declare that they have no competing interests.

                Article
                10.1371/journal.pmed.0020234
                1176237
                16008507
                5e413b49-a0d2-4e5c-b350-25031e59ceeb
                Copyright: © 2005 Singh and Mills. This is an open-access article distributed under the terms of the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.
                History
                Categories
                Essay
                Epidemiology/Public Health
                HIV/AIDS
                HIV Infection/AIDS
                Infectious Diseases
                Sexual Health
                Sexually Transmitted Diseases
                Health Education (Including Prevention and Promotion)

                Medicine
                Medicine

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