The genes coding for phosphoenolpyruvate carboxykinase-1 (PCK1) and neuronal nicotinic acetylcholine receptor alpha 4 subunit (CHRNA4) map to human chromosome 20, extending the known region of homology with mouse chromosome 2.

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Abstract

The mouse genes for cytosolic phosphoenolpyruvate carboxykinase-1 (Pck-1) and neuronal nicotinic acetylcholine receptor alpha 4 subunit (Acra-4) both map to distal chromosome 2 (Siracusa et al. 1989; Bessis et al. 1990). We have utilized Southern blot analysis on human/rodent somatic cell hybrids to map the human homologues of both of these genes, PCK1 and CHRNA4, to human chromosome 20.

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Journal

Journal ID (iso-abbrev): Ann. Hum. Genet.

Title: Annals of human genetics

ISSN: 0003-4800

ISSN (Print): 0003-4800

Publication date (Electronic): Oct 1992

Volume: 56

Issue: Pt 4

Affiliations

[1 ] Department of Genetics and Biometry, University College London, England.

Article

DOI: 10.1111/j.1469-1809.1992.tb01155.x

PubMed ID: 1492743

SO-VID: 5e5d0fe3-79fd-4a04-8604-dd8790d09998

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