+1 Recommend
1 collections
      • Record: found
      • Abstract: found
      • Article: found

      Modification of the Rabbit Electroretinogram by Reserpine

      Ophthalmic Research

      S. Karger AG

      Electroretinogram, Reserpine, Rabbit, Dopamine, L-Dopa, Oscillatory components, Adrenergic neurons

      Read this article at

          There is no author summary for this article yet. Authors can add summaries to their articles on ScienceOpen to make them more accessible to a non-specialist audience.


          A single I v. dose of reserpine, 2 mg/kg, results in a substantial depression of the b-wave of the rabbit electroretinogram evoked by intense stimuli. All but one of the oscillatory components on the b-wave are suppressed, an effect which can be reversed by administering L-dopa. The amplitude of the a-wave remains essentially unchanged after reserpine, but the c-wave is markedly enhanced. The amplitude of the low voltage b-wave elicited by weak stimuli is not appreciably altered by reserpine.

          Related collections

          Author and article information

          Ophthalmic Res
          Ophthalmic Research
          S. Karger AG
          July 2004
          09 December 2009
          : 4
          : 2
          : 65-75
          Department of Physiology and Pharmacology, Duke University Medical Center, Durham, N.C.
          265957 Ophthalmic Res 1972–73;4:65–75
          © 1972 S. Karger AG, Basel

          Copyright: All rights reserved. No part of this publication may be translated into other languages, reproduced or utilized in any form or by any means, electronic or mechanical, including photocopying, recording, microcopying, or by any information storage and retrieval system, without permission in writing from the publisher. Drug Dosage: The authors and the publisher have exerted every effort to ensure that drug selection and dosage set forth in this text are in accord with current recommendations and practice at the time of publication. However, in view of ongoing research, changes in government regulations, and the constant flow of information relating to drug therapy and drug reactions, the reader is urged to check the package insert for each drug for any changes in indications and dosage and for added warnings and precautions. This is particularly important when the recommended agent is a new and/or infrequently employed drug. Disclaimer: The statements, opinions and data contained in this publication are solely those of the individual authors and contributors and not of the publishers and the editor(s). The appearance of advertisements or/and product references in the publication is not a warranty, endorsement, or approval of the products or services advertised or of their effectiveness, quality or safety. The publisher and the editor(s) disclaim responsibility for any injury to persons or property resulting from any ideas, methods, instructions or products referred to in the content or advertisements.

          Page count
          Pages: 11


          Comment on this article