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      Reproducibility of positive results for the detection of serum galactomannan by Platelia™ aspergillus EIA.

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          Abstract

          Galactomannan (GM) was recently included in consensus guidelines as an indirect mycological criterion for the diagnosis of invasive aspergillosis. Currently, there is an enzyme immunoassay available to detect GM in biological samples, the Platelia™ Aspergillus EIA. In this study, the reproducibility of positive results obtained using this assay was evaluated using serum samples from neutropenic patients. A trend toward lower values was observed, and 55 %(27/49) of positive results were negative after retesting. A low reproducibility of positive results for the detection of GM in serum was observed.

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          Author and article information

          Journal
          Mycopathologia
          Mycopathologia
          Springer Nature America, Inc
          1573-0832
          0301-486X
          Oct 2013
          : 176
          : 3-4
          Affiliations
          [1 ] Immunology Service of Infectious Diseases (ISID), Federal University of Bahia, Salvador, Bahia, Brazil, kellypedroza@hotmail.com.
          Article
          10.1007/s11046-013-9670-z
          23943403
          5e6c5155-c998-4b9c-85cc-675bca0a8797
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