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      Strategies for early detection of chronic Q-fever: a systematic review.

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          Abstract

          Chronic Q-fever, a condition with high morbidity and mortality, may develop after an acute infection with Coxiella burnetii (acute Q-fever). Several strategies have been suggested for early detection of chronic Q-fever, focusing on follow-up of known acute Q-fever patients and detection of asymptomatic or unknown chronic infections. As there is no international standard or consensus, the aims of this study were to summarise the available literature and assess the evidence for different follow-up and screening strategies.

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          Author and article information

          Journal
          Eur J Clin Invest
          European journal of clinical investigation
          Wiley
          1365-2362
          0014-2972
          Jun 2013
          : 43
          : 6
          Affiliations
          [1 ] Centre for Infectious Disease Control, National Institute for Public Health and the Environment, Bilthoven, the Netherlands. l.wielders@jbz.nl
          Article
          10.1111/eci.12073
          23550525
          5e776784-1562-4eb0-8c19-6563cf17ec44
          © 2013 Stichting European Society for Clinical Investigation Journal Foundation. Published by John Wiley & Sons Ltd.
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