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      Is frozen embryo transfer better for mothers and babies? Can cumulative meta-analysis provide a definitive answer?

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          Abstract

          <p class="first" id="d7047608e111">Initial observational studies and a systematic review published 5 years ago have suggested that obstetric and perinatal outcomes are better in offspring conceived following frozen rather than fresh embryo transfers, with reduced risks of preterm birth, small for gestational age, low birth weight and pre-eclampsia. More recent primary studies are beginning to challenge some of these findings. We therefore conducted an updated systematic review and cumulative meta-analysis to examine if these results have remained consistent over time. </p>

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          Author and article information

          Journal
          Human Reproduction Update
          Oxford University Press (OUP)
          1355-4786
          1460-2369
          January 01 2018
          January 01 2018
          : 24
          : 1
          : 35-58
          Article
          10.1093/humupd/dmx031
          29155965
          5eac6eec-304a-4327-a5cf-e099f239c507
          © 2018
          History

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