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      Availability of Protein Amino Groups in Senile Nuclear Cataract

      Ophthalmic Research

      S. Karger AG

      Senile nuclear cataract, Lysine availability, ε-Amino groups, Sulfhydryl groups

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          Abstract

          The reagent 2, 4, 6-trinitrobenzenesulfonic acid was used to probe the status of protein amino groups in the nuclei of control (cortical cataract) and advanced senile nuclear cataractous lenses. There was no significant difference in the content of reactive amino groups in control and senile nuclear cataractous lenses. The great majority, if not all, of the ε-amino groups of lysine residues in lens protein exist in the free form. There was no detectable difference in the protein sulfhydryl content of control and advanced senile nuclear cataractous lens proteins after reduction with mercaptoethanol.

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          Author and article information

          Journal
          ORE
          Ophthalmic Res
          10.1159/issn.0030-3747
          Ophthalmic Research
          S. Karger AG
          0030-3747
          1423-0259
          1983
          1983
          04 December 2009
          : 15
          : 1
          : 38-41
          Affiliations
          Clinical Pharmacology and Therapeutics Unit, Austin Hospital, Heidelberg, Vic, Australia
          Article
          265235 Ophthalmic Res 1983;15:38–41
          10.1159/000265235
          6406954
          © 1983 S. Karger AG, Basel

          Copyright: All rights reserved. No part of this publication may be translated into other languages, reproduced or utilized in any form or by any means, electronic or mechanical, including photocopying, recording, microcopying, or by any information storage and retrieval system, without permission in writing from the publisher. Drug Dosage: The authors and the publisher have exerted every effort to ensure that drug selection and dosage set forth in this text are in accord with current recommendations and practice at the time of publication. However, in view of ongoing research, changes in government regulations, and the constant flow of information relating to drug therapy and drug reactions, the reader is urged to check the package insert for each drug for any changes in indications and dosage and for added warnings and precautions. This is particularly important when the recommended agent is a new and/or infrequently employed drug. Disclaimer: The statements, opinions and data contained in this publication are solely those of the individual authors and contributors and not of the publishers and the editor(s). The appearance of advertisements or/and product references in the publication is not a warranty, endorsement, or approval of the products or services advertised or of their effectiveness, quality or safety. The publisher and the editor(s) disclaim responsibility for any injury to persons or property resulting from any ideas, methods, instructions or products referred to in the content or advertisements.

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          Pages: 4
          Categories
          Original Paper

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