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      Xanthine oxidase inhibition for the treatment of cardiovascular disease: a systematic review and meta-analysis.

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          Abstract

          Xanthine oxidase inhibition (XOI) reduces oxidative stress in the vasculature. Moreover it reduces uric acid levels, a risk factor for the development of cardiovascular disease. As such, XOI holds a potentially dual mechanism for the treatment of cardiovascular disease.

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          Author and article information

          Journal
          Cardiovasc Ther
          Cardiovascular therapeutics
          Wiley
          1755-5922
          1755-5914
          Aug 2012
          : 30
          : 4
          Affiliations
          [1 ] College of Medicine, Veterinary & Life Sciences, Institute of Cardiovascular & Medical Sciences, University of Glasgow, Glasgow, UK. peter.higgins@glasgow.ac.uk
          Article
          10.1111/j.1755-5922.2011.00277.x
          22099531
          5ebd7c46-1164-4dc6-af81-a4bc0849bde3
          © 2011 Blackwell Publishing Ltd.
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