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      Intratendinous adipose-derived stromal vascular fraction (SVF) injection provides a safe, efficacious treatment for Achilles tendinopathy: results of a randomized controlled clinical trial at a 6-month follow-up.

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          Abstract

          Although platelet-rich plasma (PRP) injection has shown controversial results for the treatment of Achilles tendinopathy, it remains the most used biological treatment. Recent findings seem to demonstrate that the stromal vascular fraction (SVF) within adipose tissue may counteract the impaired tendon homeostasis. The aim of this study was to prospectively compare the efficacy of PRP and SVF injection for the treatment of non-insertional Achilles tendinopathy.

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          Author and article information

          Journal
          Knee Surg Sports Traumatol Arthrosc
          Knee surgery, sports traumatology, arthroscopy : official journal of the ESSKA
          Springer Nature
          1433-7347
          0942-2056
          Mar 01 2017
          Affiliations
          [1 ] CASCO Department, Istituto Ortopedico Galeazzi, Via Riccardo Galeazzi 4, 20161, Milano, Italy. fusuelli@gmail.com.
          [2 ] USPeC, Istituto Ortopedico Galeazzi, Via Riccardo Galeazzi 4, 20161, Milano, Italy.
          [3 ] CASCO Department, Istituto Ortopedico Galeazzi, Via Riccardo Galeazzi 4, 20161, Milano, Italy.
          [4 ] Universita' degli Studi di Milano, Milano, Italy.
          [5 ] Orthopaedic Biotechnology Laboratory, Istituto Ortopedico Galeazzi, Via Riccardo Galeazzi 4, 20161, Milano, Italy.
          [6 ] Plastic Surgery Department, Istituto Ortopedico Galeazzi, Via Riccardo Galeazzi 4, 20161, Milano, Italy.
          Article
          10.1007/s00167-017-4479-9
          10.1007/s00167-017-4479-9
          28251260
          5ec0016a-db70-47c3-b693-468a7a73a533
          History

          Achilles tendinopathy,Achilles tendon,Adipose-derived mesenchymal stem cells,PRP,Stromal vascular fraction (SVF)

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