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      MicroRNA-21 regulates expression of the PTEN tumor suppressor gene in human hepatocellular cancer.

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          Abstract

          microRNAs (miRNAs) are short noncoding RNAs that regulate gene expression negatively. Although a role for aberrant miRNA expression in cancer has been postulated, the pathophysiologic role and relevance of aberrantly expressed miRNA to tumor biology has not been established.

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          Author and article information

          Journal
          Gastroenterology
          Gastroenterology
          Elsevier BV
          0016-5085
          0016-5085
          Aug 2007
          : 133
          : 2
          Affiliations
          [1 ] Department of Internal Medicine, Scott and White Clinic, Texas A&M University System Health Science Center College of Medicine, Temple, Texas, USA.
          Article
          S0016-5085(07)01002-5 NIHMS130221
          10.1053/j.gastro.2007.05.022
          4285346
          17681183
          5f97df92-55a0-4f45-b96f-e09db90d0fb9
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