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      Effect of Gender on the Left Ventricular Diastolic Performance during Isometric Handgrip Exercise in Normal Individuals

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          Abstract

          To evaluate the effects of gender and isometric handgrip exercise on left ventricular diastolic function in normal individuals, atrial and rapid filling fraction were investigated using M-mode echocardiography in 35 postmenopausal women and 31 age-matched men. There were no significant differences in heart rate, mean blood pressure, atrial filling fraction, and rapid filling fraction at rest between women and men. When the amount of change in hemodynamic variable during exercise was compared, there were no significant differences in heart rate and mean blood pressure between women and men. But the increase in atrial filling fraction and the decrease in rapid filling fraction were significantly larger in women than in men. These data suggest that left ventricular diastolic function is restricted in postmenopausal women, and left atrial booster pump action is mobilized when afterload is increased during isometric handgrip exercise.

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          Author and article information

          Journal
          CRD
          Cardiology
          10.1159/issn.0008-6312
          Cardiology
          S. Karger AG
          0008-6312
          1421-9751
          1994
          1994
          18 November 2008
          : 84
          : 4-5
          : 255-260
          Affiliations
          Second Department of Internal Medicine, Kansai Medical University, Osaka, Japan
          Article
          176408 Cardiology 1994;84:255–260
          10.1159/000176408
          8187109
          © 1994 S. Karger AG, Basel

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          Page count
          Pages: 6
          Categories
          General Cardiology

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