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      A combination of flexible and rigid bronchoscopy in the successful removal of a residual fish bone from a peripheral bronchus: A case report

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          Abstract

          Although rigid bronchoscopy remains the gold standard for the management of foreign body (FB) inhalation, sometimes it still misses residual FBs. Inhalation of sharp FBs by infants is an uncommon but hazardous occurrence, which presents a significant challenge and demands expertise in therapeutic bronchoscopy. Particularly, residual sharp FBs in the peripheral tracheobronchial tree may pose challenging management problems for bronchoscopists. Herein, we describe the case of 1-year-old girl, who presented with persistent atelectasis in the left lower lobe for 20 days without responding to antibiotic therapy after removal of fish bone by rigid bronchoscopy at local hospital. Flexible bronchoscopy at our department showed a residual fish bone in the outer basal segment of the left lower lobe. A combined flexible and rigid bronchoscopy was then applied, and a fish bone measuring 1.5 cm in length was extracted on multiple attempts without any complications. Thus, our reports demonstrated that removal of challenging residual sharp FBs in the distal airways is possible with the aid of combined flexible and rigid bronchoscopy by an experienced multidisciplinary team. Additionally, a physician should pay special attention to abnormal chest images after removal of FBs.

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          Most cited references31

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          High-performance medicine: the convergence of human and artificial intelligence

          Eric Topol (2019)
          The use of artificial intelligence, and the deep-learning subtype in particular, has been enabled by the use of labeled big data, along with markedly enhanced computing power and cloud storage, across all sectors. In medicine, this is beginning to have an impact at three levels: for clinicians, predominantly via rapid, accurate image interpretation; for health systems, by improving workflow and the potential for reducing medical errors; and for patients, by enabling them to process their own data to promote health. The current limitations, including bias, privacy and security, and lack of transparency, along with the future directions of these applications will be discussed in this article. Over time, marked improvements in accuracy, productivity, and workflow will likely be actualized, but whether that will be used to improve the patient-doctor relationship or facilitate its erosion remains to be seen.
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            Artificial intelligence in digital pathology — new tools for diagnosis and precision oncology

            In the past decade, advances in precision oncology have resulted in an increased demand for predictive assays that enable the selection and stratification of patients for treatment. The enormous divergence of signalling and transcriptional networks mediating the crosstalk between cancer, stromal and immune cells complicates the development of functionally relevant biomarkers based on a single gene or protein. However, the result of these complex processes can be uniquely captured in the morphometric features of stained tissue specimens. The possibility of digitizing whole-slide images of tissue has led to the advent of artificial intelligence (AI) and machine learning tools in digital pathology, which enable mining of subvisual morphometric phenotypes and might, ultimately, improve patient management. In this Perspective, we critically evaluate various Al-based computational approaches for digital pathology, focusing on deep neural networks and ‘hand-crafted’ feature-based methodologies. We aim to provide a broad framework for incorporating AI and machine learning tools into clinical oncology, with an emphasis on biomarker development. We discuss some of the challenges relating to the use of AI, including the need for well-curated validation datasets, regulatory approval and fair reimbursement strategies. Finally, we present potential future opportunities for precision oncology.
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              Airway foreign bodies: A critical review for a common pediatric emergency.

              Airway foreign bodies (AFBs) is an interdisciplinary area between emergency medicine, pediatrics and otolaryngology. It is a life-threatening condition that is not infrequently seen; however, it is poorly covered in medical literature. Accidental aspiration of an element into airways is a widespread clinical scenario among children under 3 years, predominantly males. Moreover, it is the leading cause of infantile deaths and the fourth one among preschool children.

                Author and article information

                Contributors
                Journal
                Front Pediatr
                Front Pediatr
                Front. Pediatr.
                Frontiers in Pediatrics
                Frontiers Media S.A.
                2296-2360
                21 February 2023
                2023
                : 11
                : 1114043
                Affiliations
                [ 1 ]Department of Pulmonology, Children’s Hospital, Zhejiang University School of Medicine, National Clinical Research Center for Child Health , Hangzhou, China
                [ 2 ]Department of Endoscopy Center, Children’s Hospital, Zhejiang University School of Medicine, National Clinical Research Center for Child Health , Hangzhou, China
                Author notes

                Edited by: Angelo Montana, University of Catania, Italy

                Reviewed by: Martina Bevacqua, Necker-Enfants Malades Hospital, France Ginevra Malta, University of Palermo, Italy

                [* ] Correspondence: Zhimin Chen zmchen@ 123456zju.edu.cn
                [ † ]

                These authors have contributed equally to this work

                Specialty Section: This article was submitted to Pediatric Surgery, a section of the journal Frontiers in Pediatrics

                Article
                10.3389/fped.2023.1114043
                9989009
                36896398
                605b33b7-bec9-488c-b06b-b66f6bb19499
                © 2023 Shao, Li, He, Wu and Chen.

                This is an open-access article distributed under the terms of the Creative Commons Attribution License (CC BY). The use, distribution or reproduction in other forums is permitted, provided the original author(s) and the copyright owner(s) are credited and that the original publication in this journal is cited, in accordance with accepted academic practice. No use, distribution or reproduction is permitted which does not comply with these terms.

                History
                : 02 December 2022
                : 06 February 2023
                Page count
                Figures: 1, Tables: 0, Equations: 0, References: 31, Pages: 0, Words: 0
                Funding
                Funded by: Zhejiang Provincial Natural Science Foundation, doi 10.13039/501100004731;
                Award ID: LQ20H190006
                This work was supported by the grant from Zhejiang Provincial Natural Science Foundation (grant no. LQ20H190006).
                Categories
                Pediatrics
                Case Report

                flexible bronchoscopy,rigid bronchoscopy,foreign body,inhalation,case report

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