3
views
0
recommends
+1 Recommend
0 collections
    0
    shares
      • Record: found
      • Abstract: found
      • Article: not found

      Anti-inflammatory therapeutics for the treatment of atherosclerosis.

      Nature reviews. Drug discovery

      Animals, Anti-Inflammatory Agents, pharmacology, therapeutic use, Atherosclerosis, complications, drug therapy, physiopathology, Cardiovascular Diseases, etiology, prevention & control, Drug Delivery Systems, Drug Design, Humans, Inflammation

      Read this article at

      ScienceOpenPublisherPMC
      Bookmark
          There is no author summary for this article yet. Authors can add summaries to their articles on ScienceOpen to make them more accessible to a non-specialist audience.

          Abstract

          Atherosclerosis is the primary cause of heart disease and stroke and is thus the underlying pathology of the leading causes of death in the western world. Although risk can be reduced by lowering lipid levels, the equally important contribution of inflammation to the development of cardiovascular disease is not adequately addressed by existing therapies. Here, we summarize the evidence supporting a role for inflammation in the pathogenesis of atherosclerosis, discuss agents that are currently in the clinic and provide a perspective on the challenges faced in the development of drugs that target vascular inflammation.

          Related collections

          Author and article information

          Journal
          21532566
          3947588
          10.1038/nrd3444

          Comments

          Comment on this article