Prenylamine-Induced Ventricular Arrhythmias and Syncopal Attacks with Q-T Prolongation

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Abstract

A 70-year-old man, on prenylamine for exertional angina, complained of syncopal attacks which seemed to be caused by bursts of ventricular tachycardia associated with Q-T prolongation. These symptoms disappeared after treatment with lignocaine, and the Q-T interval gradually returned to normal when prenylamine was stopped. This communication emphasizes the possibility of the occurrence of Q-T prolongation with associated ventricular arrhythmias in patients treated with prenylamine and the usefulness of a cautious trial with lignocaine in ventricular arrhythmias linked to Q-T prolongation.

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Journal ID (publisher-id): CRD

Journal ID (nlm-ta): Cardiology

Journal ID (doi): 10.1159/issn.0008-6312

Title: Cardiology

Publisher: S. Karger AG

ISSN (Print): 0008-6312

ISSN (Electronic): 1421-9751

Publication date Subscription-year: 1980

Publication date (Print): 1980

Publication date (Electronic): 07 November 2008

Volume: 66

Issue: 4

Pages: 199-203

Affiliations

II Divisione Medicina Interna, Ospedale Generale ‘F. Lotti’, Pontedera, Pisa

Article

Publisher ID: 170867 Other ID: Cardiology 1980;66:199–203

DOI: 10.1159/000170867

PubMed ID: 7448836

SO-VID: 6079322e-ede9-4328-b388-dedc44150865

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Prenylamine-Induced Ventricular Arrhythmias and Syncopal Attacks with Q-T Prolongation

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Karger: Cardiovascular System

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