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      Assessment of glomerular filtration rate measurement with plasma sampling: a technical review.

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          Abstract

          This article reviews available radionuclide-based techniques for glomerular filtration rate (GFR) measurement, focusing on clinical indications for GFR measurement, ideal GFR radiopharmaceutical tracer properties, and the 2 most common tracers in clinical use. Methods for full, 1-compartment, and single-sample renal clearance characterization are discussed. GFR normalization and the role of GFR measurement in chemotherapy dosing are also considered.

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          Author and article information

          Journal
          J Nucl Med Technol
          Journal of nuclear medicine technology
          1535-5675
          0091-4916
          Jun 2013
          : 41
          : 2
          Affiliations
          [1 ] Department of Medical Physics, St. James's University Hospital, Leeds, United Kingdom. awm@medphysics.leeds.ac.uk
          Article
          jnmt.113.121004
          10.2967/jnmt.113.121004
          23658207
          607c1c20-3d98-449c-a3df-3ec515ceaa7c
          History

          GFR measurement,GFR normalization,glomerular filtration rate,radiopharmaceutical tracer,technical review

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