Hot Topics in Research: Preventive Neuroradiology in Brain Aging and Cognitive Decline.

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Abstract

Preventive neuroradiology is a new concept supported by growing literature. The main rationale of preventive neuroradiology is the application of multimodal brain imaging toward early and subclinical detection of brain disease and subsequent preventive actions through identification of modifiable risk factors. An insightful example of this is in the area of age-related cognitive decline, mild cognitive impairment, and dementia with potentially modifiable risk factors such as obesity, diet, sleep, hypertension, diabetes, depression, supplementation, smoking, and physical activity. In studying this link between lifestyle and cognitive decline, brain imaging markers may be instrumental as quantitative measures or even indicators of early disease. The purpose of this article is to provide an overview of the major studies reflecting how lifestyle factors affect the brain and cognition aging. In this hot topics review, we will specifically focus on obesity and physical activity.

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Journal

Journal ID (iso-abbrev): AJNR Am J Neuroradiol

Title: AJNR. American journal of neuroradiology

Publisher: American Society of Neuroradiology (ASNR)

ISSN (Electronic): 1936-959X

ISSN (Print): 0195-6108

Publication date (Electronic): Oct 2015

Volume: 36

Issue: 10

Affiliations

[1 ] From the Departments of Radiology (C.A.R., S.H.W., T.A.H., N.S.) cyrusraji@gmail.com.

[2 ] Psychiatry (H.E., G.S.) Discipline of Psychiatry (H.E., B.T.B.), University of Adelaide, Adelaide, South Australia, Australia.

[3 ] From the Departments of Radiology (C.A.R., S.H.W., T.A.H., N.S.).

[4 ] Neurology (D.E.B.).

[5 ] School of Medicine (S.M.), Deakin University, Geelong, Victoria, Australia.

[6 ] Department of Radiology (M.L.).

[7 ] Psychiatry (H.E., G.S.).

[8 ] Laboratory of Neuroimaging (P.M.T., A.W.T.), University of Southern California, Los Angeles, California.

[9 ] Department of Neurosurgery (R.M.F.), University of Pittsburgh, Pittsburgh, Pennsylvania.

[10 ] Nuclear Medicine (D.H.S.), University of California at Los Angeles Medical Center, University of California at Los Angeles, Los Angeles, California.

[11 ] Discipline of Psychiatry (H.E., B.T.B.), University of Adelaide, Adelaide, South Australia, Australia.

[12 ] Departments of Radiology and Epidemiology (M.W.V.), Erasmus University Medical Center, Rotterdam, the Netherlands.

Article

Publisher Item ID: ajnr.A4409 Mid ID: NIHMS695610

DOI: 10.3174/ajnr.A4409

PMC ID: 4600413

PubMed ID: 26045577

SO-VID: 60b3a769-94a5-4bbe-b5f0-c384b6dfb1f2

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