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      X-Ray, Light and Electron Microscopic Observations in Experimental Lymphostasis of the Liver

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          Abstract

          Experimental lymph stasis demonstrates the hepatic lymph vessel system by unfolding of the branching lymphatics. The lymphatics are limited to the interlobular connective tissue. The lymphatic wall consists of a flat endothelium without pores and without a continuous basal membrane. The endothelial cells show overlapping processes and are suspended in a net of delicate filaments. Lymph and bile stasis produce separation of the endothelial junctions. Only reversible changes of liver parenchyma are seen after pure lymphostasis. The storage of tantalum powder by the liver is reduced by the Imphostatic edema. The significance of lymph stasis resides primarily in its existence as an additional stressor. Simultaneous lymph and bile stasis definitely speeded up the cirrhotic process. The experimental models should lead to a greater emphasis of the importance of the hepatic lymphatic drainage system, and especially of lymphostasis as an important additional factor in pathogenesis of human diseases.

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          Author and article information

          Journal
          JVR
          J Vasc Res
          10.1159/issn.1018-1172
          Journal of Vascular Research
          S. Karger AG
          1018-1172
          1423-0135
          1972
          1972
          18 September 2008
          : 9
          : 1
          : 40-52
          Affiliations
          Pathologisches Institut der Universität Düsseldorf (Direktor: Prof. Dr. H. Meessen), Düsseldorf
          Article
          157914 Angiologica 1972;9:40–52
          10.1159/000157914
          © 1972 S. Karger AG, Basel

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          Page count
          Pages: 13
          Categories
          Paper

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