562
views
0
recommends
+1 Recommend
0 collections
    0
    shares
      • Record: found
      • Abstract: found
      • Article: not found

      The cell biology of neurogenesis.

      Nature reviews. Molecular cell biology
      Animals, Cell Cycle, physiology, Cell Differentiation, Cell Polarity, Central Nervous System, cytology, embryology, Humans, Mammals, Neuroglia, Neurons, Stem Cells

      Read this article at

      ScienceOpenPublisherPubMed
      Bookmark
          There is no author summary for this article yet. Authors can add summaries to their articles on ScienceOpen to make them more accessible to a non-specialist audience.

          Abstract

          During the development of the mammalian central nervous system, neural stem cells and their derivative progenitor cells generate neurons by asymmetric and symmetric divisions. The proliferation versus differentiation of these cells and the type of division are closely linked to their epithelial characteristics, notably, their apical-basal polarity and cell-cycle length. Here, we discuss how these features change during development from neuroepithelial to radial glial cells, and how this transition affects cell fate and neurogenesis.

          Related collections

          Author and article information

          Journal
          16314867
          10.1038/nrm1739

          Chemistry
          Animals,Cell Cycle,physiology,Cell Differentiation,Cell Polarity,Central Nervous System,cytology,embryology,Humans,Mammals,Neuroglia,Neurons,Stem Cells

          Comments

          Comment on this article