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      Changes in Weight and in Protein – Water Ratio of the Lens in Human Senile Cataracts

      ,

      Ophthalmic Research

      S. Karger AG

      Senile cataract, Lens weight, Lens water, Cataractogenesis, Lens growth, Lens dry weight, Human lens

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          Abstract

          Changes in wet weight, dry weight and water content have been studied in different types of senile cataract and compared With transparent control lenses. While nuclear brunescent cataractous lens show normal weight, protein and water content, cortical opacification is characterized by a progressive decrease of total lens proteins associated with important terminal alterations of the percentage of water content. Posterior subcapsular cataracts in very early stages of the disease have a significantly lower wet weight than control lenses, but a normal protein-water ratio; this is interpreted as a decreased lens growth starting far back in time and producing apparently normal lens substance. The question is raised whether this could be interpreted as a manifestation of the same pathogenetic cause which determines the appearance of this type of lens opacification.

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          Author and article information

          Journal
          ORE
          Ophthalmic Res
          10.1159/issn.0030-3747
          Ophthalmic Research
          S. Karger AG
          0030-3747
          1423-0259
          1972
          1972
          09 December 2009
          : 3
          : 2
          : 108-113
          Affiliations
          University Eye Clinic, Parma
          Article
          266175 Ophthal Res 1972;3:108–113
          10.1159/000266175
          © 1972 S. Karger AG, Basel

          Copyright: All rights reserved. No part of this publication may be translated into other languages, reproduced or utilized in any form or by any means, electronic or mechanical, including photocopying, recording, microcopying, or by any information storage and retrieval system, without permission in writing from the publisher. Drug Dosage: The authors and the publisher have exerted every effort to ensure that drug selection and dosage set forth in this text are in accord with current recommendations and practice at the time of publication. However, in view of ongoing research, changes in government regulations, and the constant flow of information relating to drug therapy and drug reactions, the reader is urged to check the package insert for each drug for any changes in indications and dosage and for added warnings and precautions. This is particularly important when the recommended agent is a new and/or infrequently employed drug. Disclaimer: The statements, opinions and data contained in this publication are solely those of the individual authors and contributors and not of the publishers and the editor(s). The appearance of advertisements or/and product references in the publication is not a warranty, endorsement, or approval of the products or services advertised or of their effectiveness, quality or safety. The publisher and the editor(s) disclaim responsibility for any injury to persons or property resulting from any ideas, methods, instructions or products referred to in the content or advertisements.

          Page count
          Pages: 6
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