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      Effect of Baduanjin exercises on elevated blood lipid levels of middle-aged and elderly individuals: protocol for a systematic review and meta-analysis of randomised controlled trials

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          Abstract

          Objective

          To assess the safety and effect on elevated blood lipid levels of Baduanjin exercises in middle-aged and elderly individuals.

          Methods

          A systematic literature search for articles up to March 2017 will be conducted using seven databases: PubMed, Embase, Cochrane Library, Chinese National Knowledge Infrastructure, Chinese Science and Technology Periodicals Database, Chinese BioMedical Database and Wanfang Data. Inclusion criteria are randomised controlled trials of Baduanjin exercises that examine blood lipid levels in middle-aged and elderly individuals. The primary outcome measures will be total cholesterol, triglycerides, low-density lipoprotein cholesterol and high-density lipoprotein cholesterol. Stata V.13.0 software will be used for data synthesis, sensitivity analysis, metaregression, subgroup analysis and risk of bias assessment. A funnel plot will be developed to evaluate reporting bias and Begg and Egger tests will be used to assess funnel plot symmetries. We will use the Grading of Recommendations Assessment, Development and Evaluation system to assess the quality of evidence.

          Ethics and dissemination

          This systematic review will be submitted to a peer-reviewed journal. Our findings will provide information about the safety of Baduanjin exercises for middle-aged and elderly individuals and their effect on elevated blood lipid levels.

          Trial registration number

          PROSPERO CRD 42017060613.

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          Most cited references19

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          An assessment by the Statin Muscle Safety Task Force: 2014 update.

          Robert S. Rosenson, Steven K Baker, Terry Jacobson … (2024)
          The National Lipid Association's Muscle Safety Expert Panel was charged with the duty of examining the definitions for statin-associated muscle adverse events, development of a clinical index to assess myalgia, and the use of diagnostic neuromuscular studies to investigate muscle adverse events. We provide guidance as to when a patient should be considered for referral to neuromuscular specialists and indications for the performance of a skeletal muscle biopsy. Based on this review of evidence, we developed an algorithm for the evaluation and treatment of patients who may be intolerant to statins as the result of adverse muscle events. The panel was composed of clinical cardiologists, clinical lipidologists, an exercise physiologist, and a neuromuscular specialist.
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            The Effect of Chinese Traditional Exercise-Baduanjin on Physical and Psychological Well-Being of College Students: A Randomized Controlled Trial

            Moyi Li, Qianying Fang, Junzhe Li … (2015)
            Background The physical and mental health of college students tends to continuously decline around the world, therefore, it is important to improve their health during college period. Baduanjin, a traditional Chinese exercise which combines movements with breath and mind, may be one of the selectable effective exercises. However, the effect of Baduanjin exercise on college students has not been established. In this study, we systematically assessed the effectiveness and safety of Baduanjin exercise on physical and mental health of college students by a rigorous randomized, parallel-controlled design. Methods A total of 222 college students from Fujian University of Traditional Chinese Medicine were recruited and randomly allocated at an equal ratio into control or Baduanjin training. Participants in control group were informed to maintain their original activity habit, and those in Baduanjin exercise group received a 12-week Baduanjin exercise training with a frequency of 1 hour per day and 5 days per week on the basis of their original activity habit. The physical and psychological outcomes, including lumbar muscle strength, lower limb proprioception function, physical fitness, as well as self-reported symptom intensity, stress, self-esteem, mood, quality of life, quality of sleep, and adverse events, were evaluated at baseline, 13 weeks (at the end of 12-week intervention), and 25 weeks (after the 12-week follow-up period). Intention-to-treat analysis was performed for the above outcomes. Results Compared with controls, significant improvements in Baduanjin exercise group at the end of 12-week intervention period were found on lower limb proprioception function (the rate of average trace error on right lower limb (%): control 23.50±5.50, Baduanjin 21.92±6.54, P=0.004; the rate of average trace error on left lower limb (%): control 22.32±6.62, Baduanjin 20.63±4.62, P=0.046), cardiorespiratory endurance (step test index: control 47.66±5.94, Baduanjin 50.07±9.30, P=0.025), flexibility (control 14.35±7.26cm, Baduanjin 15.39±6.43cm, P=0.009) and explosive force of lower limb (standing long jump test (m): control 1.77±0.24, Baduanjin 1.79±0.22, P=0.005 for adjustment baseline) in physical outcomes, and attention (Schulte Grid test (second): control 210.4±51.15, Baduanjin 192.4±47.14, P=0.034) in mental outcome. Lumbar muscle strength in Baduanjin group had been moderately enhanced but no significant difference compared to controls. No significant changes in other physical and mental outcomes, including vital capacity, blood pressure, heart rate, hand grip force, self-symptom intensity, stress, self-efficacy, quality of life, and quality of sleep, were found between groups. No adverse event was reported during the study period. Conclusion Regular Baduanjin exercise had an advantage for college students on improvement of lower limb proprioception, enhance of cardiorespiratory endurance, flexibility, explosive force of lower limb and attention, compared with usual exercise. Trial Registration Chinese Clinical Trial Registry ChiCTR-TRC-13003329 http://www.chictr.org
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              Baduanjin alleviates the symptoms of knee osteoarthritis.

              Bingchen An, Kerong Dai, Zhenan Zhu … (2008)
              To assess the feasibility and safety of using the health-promoting traditional Chinese exercise, known as Baduanjin, in treating knee osteoarthritis (OA).
              Article 0 comments Cited 44 times – based on 0 reviews     Review now
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                Author and article information

                Journal
                Journal ID (nlm-ta): BMJ Open
                Journal ID (iso-abbrev): BMJ Open
                Journal ID (hwp): bmjopen
                Journal ID (publisher-id): bmjopen
                Title: BMJ Open
                Publisher: BMJ Publishing Group (BMA House, Tavistock Square, London, WC1H 9JR )
                ISSN (Electronic): 2044-6055
                Publication date Collection: 2017
                Publication date (Electronic): 3 September 2017
                Volume: 7
                Issue: 9
                Electronic Location Identifier: e017213
                Affiliations
                [1 ] Guangzhou University of Chinese Medicine , Guangzhou
                [2 ] departmentDepartment of cardiovascular , The First Affiliated Hospital of Guangzhou University of Chinese Medicine , Guangzhou, China
                Author notes
                [Correspondence to ] Dr. Wei Wu; 3332564768@ 123456qq.com
                Article
                Publisher ID: bmjopen-2017-017213
                DOI: 10.1136/bmjopen-2017-017213
                PMC ID: 5589011
                PubMed ID: 28871023
                SO-VID: 613f1dc4-d345-4a9f-a059-95e067b77ca6
                Copyright © © Article author(s) (or their employer(s) unless otherwise stated in the text of the article) 2017. All rights reserved. No commercial use is permitted unless otherwise expressly granted.
                License:

                This is an Open Access article distributed in accordance with the terms of the Creative Commons Attribution (CC BY 4.0) license, which permits others to distribute, remix, adapt and build upon this work, for commercial use, provided the original work is properly cited. See: http://creativecommons.org/licenses/by/4.0/

                History
                Date received : 07 April 2017
                Date revision received : 22 June 2017
                Date accepted : 05 July 2017
                Funding
                Funded by: Administration of Traditional Medicine of Guangdong;
                Categories
                Subject: Complementary Medicine
                Subject: Protocol
                Subject: 1506
                Subject: 1685
                Custom metadata
                special-feature unlocked

                ScienceOpen disciplines: Medicine
                Keywords: baduanjin exercises,blood lipid levels,protocol
                Data availability:
                ScienceOpen disciplines: Medicine
                Keywords: baduanjin exercises, blood lipid levels, protocol

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