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      Surgical pathologic spread patterns of endometrial cancer. A Gynecologic Oncology Group Study.

      1 , , , , ,
      Cancer
      Wiley

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          Abstract

          The surgical pathologic features of 621 patients with Stage I carcinoma of the endometrium are presented. All patients were treated with primary surgery consisting of total abdominal hysterectomy, bilateral salpingo-oophorectomy, selective pelvic and paraaortic lymphadenectomy and peritoneal cytology. An appreciable number of patients (144-22%) with Stage I cancers have disease outside of the uterus (lymph node metastasis, adnexal disease, intraperitoneal spread and/or malignant cells in peritoneal washings). Multiple prognostic factors particularly grade and depth of invasion are related to extrauterine disease. This study adds credence to the primary surgical approach with individualized postoperative therapy as indicated.

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          Author and article information

          Journal
          Cancer
          Cancer
          Wiley
          0008-543X
          0008-543X
          Oct 15 1987
          : 60
          : 8 Suppl
          Affiliations
          [1 ] Department of Obstetrics and Gynecology, Duke University Medical Center, Durham, North Carolina.
          Article
          10.1002/1097-0142(19901015)60:8+<2035::aid-cncr2820601515>3.0.co;2-8
          3652025
          619dbce9-0e46-48dd-8aa5-e7246bd01af3
          History

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