Precision aging. Human lifespan has intrinsic limits but measurable outcomes

Abstract

A recent article by Pyrkov et al suggests that progressive loss of physical resilience to aging coincides with an absolute limit of human lifespan in the range of 120 to 150 years. Furthermore, the authors conclude that end of life is an intrinsic biological property independent of internal or external stress factors. Their analysis is based on a log-linear mortality estimate of complete blood count variables, such as neutrophil lymphocyte ratio, as single quantitive measures of the aging process correlated with physical activity data from individual tracking devices.