Blog
About

111
views
0
recommends
+1 Recommend
0 collections
    0
    shares
      • Record: found
      • Abstract: found
      • Article: not found

      Mitochondria, oxidants, and aging.

      Cell

      Yeasts, metabolism, Reactive Oxygen Species, Oxidants, physiology, Nutritional Physiological Phenomena, genetics, Mutation, Mitochondria, Free Radicals, Animals, Aging

      Read this article at

      ScienceOpenPublisherPubMed
      Bookmark
          There is no author summary for this article yet. Authors can add summaries to their articles on ScienceOpen to make them more accessible to a non-specialist audience.

          Abstract

          The free radical theory of aging postulates that the production of intracellular reactive oxygen species is the major determinant of life span. Numerous cell culture, invertebrate, and mammalian models exist that lend support to this half-century-old hypothesis. Here we review the evidence that both supports and conflicts with the free radical theory and examine the growing link between mitochondrial metabolism, oxidant formation, and the biology of aging.

          Related collections

          Author and article information

          Journal
          15734681
          10.1016/j.cell.2005.02.001

          Comments

          Comment on this article